SCHEMBL1699487

SCHEMBL1699487

CC1CC(=O)c2ccccc2C1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.57
TSHR P16473 1/20 0.52
BRD4 O60885 1/20 0.50
CREBBP Q92793 1/20 0.50
CYP19A1 P11511 1/20 0.50
STAT3 P40763 1/20 0.47
CYP2A6 P11509 1/20 0.45
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
HTR2A P28223 4/20 0.44
HTR2C P28335 4/20 0.44
HTR2B P41595 4/20 0.44
METAP1 P53582 2/20 0.43
NOS3 P29474 1/20 0.43
NOS2 P35228 1/20 0.43
S100A4 P26447 1/20 0.42
BCHE P06276 1/20 0.42
CES1 P23141 1/20 0.42
SIGMAR1 Q99720 1/20 0.42
CSNK2A2 P19784 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7712799 0.82 CYP2A6 (0.50) ACHETSHRBRD4CREBBPCYP19A1
SCHEMBL315647 0.77 BRD4 (0.54) ACHETSHRBRD4CREBBPNOS3
SCHEMBL8637686 0.76 PTPRC (0.49) BRD4CREBBPSTAT3GRM5
SCHEMBL11392307 0.75 CYP19A1 (0.50) ACHETSHRCYP19A1CYP2A6MAOA
SCHEMBL22368760 0.75 ACHE (0.47) ACHETSHRBRD4CREBBPHTR2A
SCHEMBL6256650 0.75 CYP19A1 (0.50) ACHETSHRCYP19A1CYP2A6MAOA
SCHEMBL7856214 0.75 CYP19A1 (0.50) ACHETSHRCYP19A1CYP2A6MAOA
SCHEMBL1699495 0.75 ACHE (0.47) ACHESTAT3MAOAMAOBHTR2A
SCHEMBL10346056 0.75 ACHE (0.47) ACHETSHRBRD4CYP19A1CYP2A6
SCHEMBL12433394 0.75 ACHE (0.61) ACHESTAT3MAOAMAOBHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250233206-A1 NON-AQUEOUS ELECTROLYTE SOLUTION AND NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2025-07-17 US disclosed
US-12315883-B2 Non-aqueous electrolyte solution and non-aqueous electrolyte secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2025-05-27 US disclosed
US-20230395857-A1 NON-AQUEOUS ELECTROLYTE SOLUTION AND NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2023-12-07 US disclosed
CN-117142938-A Method for preparing 1, 4-naphthoquinone compound by selectively oxidizing aromatic ketone 大连理工大学 2023-12-01 CN disclosed
US-11791499-B2 Non-aqueous electrolyte solution and non-aqueous electrolyte secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2023-10-17 US disclosed
US-20220069351-A1 NON-AQUEOUS ELECTROLYTE SOLUTION AND NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2022-03-03 US disclosed
US-11205802-B2 Non-aqueous electrolyte solution and non-aqueous electrolyte secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2021-12-21 US disclosed
CN-107108512-B Therapeutic compounds and uses thereof 基因泰克公司 2021-05-04 CN disclosed
EP-3758124-A1 NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY Mitsubishi Chemical Corporation (JP) 2020-12-30 EP disclosed
EP-3204360-B1 THERAPEUTIC COMPOUNDS AND USES THEREOF GENENTECH INC (US) 2020-08-26 EP disclosed
US-20120301797-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION, ELECTROCHEMICAL ELEMENT USING SAME, AND ALKYNYL COMPOUND USED THEREFOR UBE INDUSTRIES, LTD. (JP) 2012-11-29 US disclosed
US-20120302562-A1 4H-THIENO[3,2-C]CHROMENE-BASED INHIBITORS OF NOTUM PECTINACETYLESTERASE AND METHODS OF THEIR USE LEXICON PHARMACEUTICALS, INC. 2012-11-29 US disclosed
US-20120302562-A1 4H-THIENO[3,2-C]CHROMENE-BASED INHIBITORS OF NOTUM PECTINACETYLESTERASE AND METHODS OF THEIR USE LEXICON PHARMACEUTICALS, INC. 2012-11-29 US disclosed
WO-2012003497-A1 NAPHT- 2 -YLACETIC ACID DERIVATIVES TO TREAT AIDS GILEAD SCIENCES, INC. (US) 2012-01-05 WO disclosed
WO-2012003497-A1 NAPHT- 2 -YLACETIC ACID DERIVATIVES TO TREAT AIDS GILEAD SCIENCES, INC. (US) 2012-01-05 WO disclosed
EP-2053095-A2 Ink composition and inkjet recording method using the same Fujifilm Corporation (JP) 2009-04-29 EP disclosed
US-4977152-A For alzheimer*s disease SOCIETE ANONYME: SANOFI (FR) 1990-12-11 US disclosed
US-4590274-A Antihypertensive 1-[bis-(substituted phenyl)methyl]-4[2-(1,2,3,4-tetrahydro-substituted naphthalen-1-ylidene)ethyl]piperazines E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-05-20 US disclosed
EP-0103990-A1 Process for making diarylamines UNIROYAL, INC. (US) 1984-03-28 EP disclosed
US-4431841-A REACTING PRIMARY AROMATIC AMINES AND ALICYCLIC KETONES USING AN ACID PROMOTER AND A PLATINUM CATALYST UNIROYAL, INC. (US) 1984-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120302562-A1 4H-THIENO[3,2-C]CHROMENE-BASED INHIBITORS OF NOTUM PECTINACETYLESTERASE AND METHODS OF THEIR USE NOTUM, CES1, ACHE ACHE 3/4885TSHR 3034/4885BRD4 160/4885
US-20120301797-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION, ELECTROCHEMICAL ELEMENT USING SAME, AND ALKYNYL COMPOUND USED THEREFOR WEE2, WEE1, NOTUM ACHE 2913/4885TSHR 4661/4885BRD4 4041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.