Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | Q9HBH1 | 11/20 | 0.83 | |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289533 | 0.91 | PDF (1.00) | PDFMAPTKDM4ENPSR1MAPK1 | |
| SCHEMBL289946 | 0.84 | PDF (0.77) | PDFMAPTKDM4ENPSR1MAPK1 | |
| SCHEMBL290580 | 0.84 | PDF (0.77) | PDFMAPTKDM4ENPSR1MAPK1 | |
| SCHEMBL801251 | 0.82 | PDF (0.82) | PDFMAPTKDM4ENPSR1MAPK1 | |
| SCHEMBL290648 | 0.82 | PDF (1.00) | PDFMAPTKDM4ENPSR1MAPK1 | |
| SCHEMBL290072 | 0.82 | PDF (1.00) | PDFMAPTKDM4ENPSR1MAPK1 | |
| SCHEMBL16994964 | 0.81 | PDF (0.81) | PDFMAPTKDM4ENPSR1MAPK1 | |
| SCHEMBL290535 | 0.77 | PDF (0.65) | PDFMAPTKDM4ENPSR1MAPK1 | |
| SCHEMBL290433 | 0.77 | PDF (0.77) | PDFMAPTKDM4ENPSR1MAPK1 | |
| SCHEMBL290557 | 0.76 | PDF (0.72) | PDFMAPTKDM4ENPSR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427057-B1 | BENZOFURAN-4,5-DIONES AS SELECTIVE PEPTIDE DEFORMYLASE INHIBITORS | SLOAN KETTERING INST CANCER (US) | 2015-08-12 | — | — | EP | disclosed |