Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21709554 | 0.95 | ALDH1A1 (0.44) | EPHX2ALDH1A1CES2CES1 | |
| SCHEMBL28951478 | 0.87 | EPHX2 (0.44) | EPHX2ALDH1A1MEN1KMT2A | |
| SCHEMBL12556236 | 0.83 | EPHX2 (0.52) | EPHX2ALDH1A1CES2CES1LMNA | |
| SCHEMBL21709555 | 0.83 | EPHX2 (0.33) | EPHX2MEN1KMT2A | |
| SCHEMBL23183620 | 0.78 | EPHX2 (0.60) | EPHX2ALDH1A1CES2CES1LMNA | |
| SCHEMBL25836455 | 0.78 | EPHX2 (0.56) | EPHX2ALDH1A1CES2CES1LMNA | |
| SCHEMBL16435062 | 0.75 | ALDH1A1 (0.41) | ALDH1A1CES2CES1MEN1KMT2A | |
| SCHEMBL1357919 | 0.74 | EPHX2 (0.60) | EPHX2ALDH1A1MEN1KMT2AAKR1B1 | |
| SCHEMBL12928359 | 0.74 | ALDH1A1 (0.52) | EPHX2ALDH1A1CES2CES1LMNA | |
| SCHEMBL21709526 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2504311-B1 | ARACHIDONIC ACID ANALOGS AND METHODS FOR ANALGESIC TREATMENT USING SAME | CYTOMETIX INC (US) | 2015-08-12 | — | — | EP | disclosed |