Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.50 |
| ▸ | RCOR1 | Q9UKL0 | 4/20 | 0.50 |
| ▸ | SMOX | Q9NWM0 | 2/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 4/20 | 0.34 |
| ▸ | BTK | Q06187 | 4/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | EIF2AK1 | Q9BQI3 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18353782 | 0.87 | KDM1A (0.45) | KDM1ARCOR1SMOXAHRLCK | |
| SCHEMBL16995651 | 0.84 | KDM1A (0.71) | KDM1ARCOR1SMOXLCKBTK | |
| SCHEMBL16995655 | 0.81 | KDM1A (0.50) | KDM1ARCOR1SMOXLCKBTK | |
| SCHEMBL16995649 | 0.80 | KDM1A (0.72) | KDM1ARCOR1SMOXLCKBTK | |
| SCHEMBL16995650 | 0.79 | KDM1A (0.57) | KDM1ARCOR1SMOXLCKBTK | |
| SCHEMBL16995667 | 0.77 | SMOX (0.72) | KDM1ARCOR1SMOXLCKBTK | |
| SCHEMBL16995654 | 0.75 | KDM1A (0.50) | KDM1ARCOR1SMOXLCKBTK | |
| SCHEMBL16995652 | 0.75 | KDM1A (0.44) | KDM1ARCOR1SMOXLCKBTK | |
| SCHEMBL18353607 | 0.70 | KDM1A (0.64) | KDM1ARCOR1SMOXLCKBTK | |
| SCHEMBL16995687 | 0.68 | KDM1A (0.50) | KDM1ARCOR1SMOXGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170001968-A1 | AMINOTRIAZOLE- AND AMINOTETRAZOLE-BASED KDM1A INHIBITORS AS EPIGENETIC MODULATORS | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2017-01-05 | — | — | US | disclosed |
| US-20170001968-A1 | AMINOTRIAZOLE- AND AMINOTETRAZOLE-BASED KDM1A INHIBITORS AS EPIGENETIC MODULATORS | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2017-01-05 | — | — | US | disclosed |
| WO-2015120281-A1 | AMINOTRIAZOLE- AND AMINOTETRAZOLE-BASED KDM1A INHIBITORS AS EPIGENETIC MODULATORS | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2015-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170001968-A1 | AMINOTRIAZOLE- AND AMINOTETRAZOLE-BASED KDM1A INHIBITORS AS EPIGENETIC MODULATORS | KDM1A, KDM1B, KDM3A | KDM1A 1/4885RCOR1 488/4885SMOX 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.