⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20419110 | 1.00 | — | — | |
| SCHEMBL21976773 | 1.00 | — | — | |
| SCHEMBL2614700 | 1.00 | — | — | |
| SCHEMBL2614697 | 0.79 | — | — | |
| SCHEMBL1699642 | 0.79 | — | — | |
| SCHEMBL19068391 | 0.79 | — | — | |
| SCHEMBL1699644 | 0.79 | — | — | |
| SCHEMBL2614695 | 0.79 | — | — | |
| SCHEMBL15362747 | 0.79 | — | — | |
| SCHEMBL19543056 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170143631-A1 | LIPID FORMULATION | ARBUTUS BIOPHARMA CORPORATION (CA) | 2017-05-25 | — | — | US | disclosed |
| US-9593335-B2 | Small interference RNAs, uses thereof and method for inhibiting the expression of PLK1 gene | Suzhou Ribo Life Science Co., Ltd. (CN) | 2017-03-14 | — | — | US | disclosed |
| US-20160289687-A1 | SMALL INTERFERENCE RNAS, USES THEREOF AND METHOD FOR INHIBITING THE EXPRESSION OF PLK1 GENE | Suzhou Ribo Life Science Co., Ltd. (CN) | 2016-10-06 | — | — | US | disclosed |
| US-8563710-B2 | Modified oligonucleotide and its preparation and application | BIOMICS BIOTECHNOLOGIES CO., LTD. (CN) | 2013-10-22 | — | — | US | disclosed |
| US-20120088815-A1 | Modified Oligonucleotide and Its Preparation and Application | BIOMICS BIOTECHNOLOGIES CO. LTD (CN) | 2012-04-12 | — | — | US | disclosed |