⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1699642 | 1.00 | — | — | |
| SCHEMBL25504579 | 1.00 | — | — | |
| SCHEMBL19068391 | 1.00 | — | — | |
| SCHEMBL10072494 | 0.85 | — | — | |
| SCHEMBL19543056 | 0.83 | — | — | |
| SCHEMBL19068316 | 0.83 | — | — | |
| SCHEMBL15025160 | 0.83 | — | — | |
| SCHEMBL769699 | 0.83 | — | — | |
| SCHEMBL1699657 | 0.83 | — | — | |
| SCHEMBL26254814 | 0.82 | ALDH1A1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9694077-B2 | Lipid compositions | ARBUTUS BIOPHARMA CORPORATION (CA) | 2017-07-04 | — | — | US | disclosed |
| US-9540682-B2 | Double-stranded nucleic acid, use and kit thereof in ribonuclease detection | Suzhou Ribo Life Science Co., Ltd. (CN) | 2017-01-10 | — | — | US | disclosed |
| US-20160274089-A1 | SCREENING METHOD FOR SELECTED AMINO-LIPID-CONTAINING COMPOSITIONS | ARBUTUS BIOPHARMA CORPORATION (CA) | 2016-09-22 | — | — | US | disclosed |
| US-20160272967-A1 | NUCLEIC ACID, PHARMACEUTICAL COMPOSITION AND USES THEREOF | Suzhou Ribo Life Science Co., Ltd. (CN) | 2016-09-22 | — | — | US | disclosed |
| US-9394234-B2 | Lipid formulations | ARBUTUS BIOPHARMA CORPORATION (CA) | 2016-07-19 | — | — | US | disclosed |
| US-9328348-B2 | Small interference RNAs, uses thereof and method for inhibiting the expression of plk1 gene | Suzhou Ribo Life Science Co., Ltd. (CN) | 2016-05-03 | — | — | US | disclosed |
| US-20160095924-A1 | AMINO LIPIDS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2016-04-07 | — | — | US | disclosed |
| US-9139554-B2 | Amino lipids and methods for the delivery of nucleic acids | TEKMIRA PHARMACEUTICALS CORPORATION (CA) | 2015-09-22 | — | — | US | disclosed |
| US-20150190515-A1 | LIPID COMPOSITIONS | ARBUTUS BIOPHARMA CORPORATION (CA) | 2015-07-09 | — | — | US | disclosed |
| US-20150166465-A1 | LIPID FORMULATIONS | BANK OF AMERICA, N.A. | 2015-06-18 | — | — | US | disclosed |
| US-20120225434-A1 | SCREENING METHOD FOR SELECTED AMINO LIPID-CONTAINING COMPOSITIONS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-09-06 | — | — | US | disclosed |
| US-20120183602-A1 | LIPID FORMULATION | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-07-19 | — | — | US | disclosed |
| US-20120128760-A1 | LIPID COMPOSITIONS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-05-24 | — | — | US | disclosed |
| US-20120101148-A1 | LIPID FORMULATION | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-04-26 | — | — | US | disclosed |
| US-8158601-B2 | Lipid formulation | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-04-17 | — | — | US | disclosed |
| US-20110256175-A1 | AMINO LIPIDS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2011-10-20 | — | — | US | disclosed |
| US-20110117125-A1 | COMPOSITIONS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS | TEKMIRA PHARMACEUTICALS CORPORATION (CA) | 2011-05-19 | — | — | US | disclosed |
| US-20110097720-A1 | SCREENING METHOD FOR SELECTED AMINO LIPID-CONTAINING COMPOSITIONS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2011-04-28 | — | — | US | disclosed |
| US-20100324120-A1 | LIPID FORMULATION | BANK OF AMERICA, N.A. | 2010-12-23 | — | — | US | disclosed |
| US-20100222417-A1 | Compostions and methods for enhancing oligonucleotide delivery across and into epithelial tissues | ALNYLAM PHARMACEUTICALS (US) | 2010-09-02 | — | — | US | disclosed |