Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13066890 | 0.90 | MEN1 (0.50) | MEN1KMT2AALDH1A1NPSR1HTT | |
| SCHEMBL16998632 | 0.84 | MEN1 (0.48) | MEN1KMT2AALDH1A1HTTLMNA | |
| SCHEMBL16998612 | 0.84 | MEN1 (0.56) | MEN1KMT2AALDH1A1NPSR1HTT | |
| SCHEMBL16998631 | 0.83 | MEN1 (0.54) | MEN1KMT2AALDH1A1NPSR1HTT | |
| SCHEMBL21338202 | 0.80 | MEN1 (0.64) | MEN1KMT2AALDH1A1NPSR1HTT | |
| SCHEMBL843641 | 0.79 | MEN1 (0.50) | MEN1KMT2AALDH1A1NPSR1HTT | |
| SCHEMBL21338246 | 0.77 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1NPSR1LMNA | |
| SCHEMBL844421 | 0.76 | KMT2A (0.47) | MEN1KMT2AALDH1A1NPSR1HTT | |
| SCHEMBL844342 | 0.75 | MEN1 (0.40) | MEN1KMT2AALDH1A1NPSR1HTT | |
| Hydrochloric Acid SCHEMBL844158 | 0.75 | KMT2A (0.46) | MEN1KMT2AALDH1A1NPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150225423-A1 | PYRIMIDINES AS NOVEL THERAPEUTIC AGENTS | UNIVERSITé LAVAL (CA) | 2015-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150225423-A1 | PYRIMIDINES AS NOVEL THERAPEUTIC AGENTS | TYMS, P2RX2, TYMP | MEN1 4378/4885KMT2A 3590/4885ALDH1A1 577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.