Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.40 |
| ▸ | TUBB | P07437 | 5/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16999955 | 0.94 | CYP3A4 (0.40) | PTGS1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16999930 | 0.92 | TUBB4A (0.43) | PTGS1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16999931 | 0.88 | PTGS1 (0.43) | PTGS1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL18241803 | 0.86 | PTGS1 (0.42) | PTGS1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16999939 | 0.86 | CYP3A4 (0.42) | PTGS1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL18241815 | 0.86 | TUBB4A (0.45) | PTGS1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16999932 | 0.85 | PTGS1 (0.45) | PTGS1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19193056 | 0.81 | CYP3A4 (0.40) | PTGS1CYP3A4MAPK1MAOAMAOB | |
| SCHEMBL16999943 | 0.81 | CYP3A4 (0.40) | PTGS1CYP3A4MAPK1MAOAMAOB | |
| SCHEMBL19410286 | 0.81 | CYP3A4 (0.44) | PTGS1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10370349-B2 | Functionalised benzopyran compounds and use thereof | Kazia Therapeutics Limited (AU) | 2019-08-06 | — | — | US | disclosed |
| US-20180141925-A1 | FUNCTIONALISED BENZOPYRAN COMPOUNDS AND USE THEREOF | Kazia Therapeutics Limited (AU) | 2018-05-24 | — | — | US | disclosed |
| US-20180141925-A1 | FUNCTIONALISED BENZOPYRAN COMPOUNDS AND USE THEREOF | Kazia Therapeutics Limited (AU) | 2018-05-24 | — | — | US | disclosed |
| US-9701655-B2 | Functionalised benzopyran compounds and use thereof | NOVOGEN LIMITED (AU) | 2017-07-11 | — | — | US | disclosed |
| US-9701655-B2 | Functionalised benzopyran compounds and use thereof | NOVOGEN LIMITED (AU) | 2017-07-11 | — | — | US | disclosed |
| US-20160340329-A1 | FUNCTIONALISED BENZOPYRAN COMPOUNDS AND USE THEREOF | VIVESTO AB (SE) | 2016-11-24 | — | — | US | disclosed |
| US-20160340329-A1 | FUNCTIONALISED BENZOPYRAN COMPOUNDS AND USE THEREOF | VIVESTO AB (SE) | 2016-11-24 | — | — | US | disclosed |
| WO-2015117202-A1 | FUNCTIONALISED BENZOPYRAN COMPOUNDS AND USE THEREOF | NOVOGEN LIMITED (AU) | 2015-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141925-A1 | FUNCTIONALISED BENZOPYRAN COMPOUNDS AND USE THEREOF | BRCA1, BRAP, EP300 | PTGS1 1785/4885TUBB4A 1400/4885TUBB 1824/4885 |
| US-20160340329-A1 | FUNCTIONALISED BENZOPYRAN COMPOUNDS AND USE THEREOF | BRCA1, VHL, NQO1 | PTGS1 205/4885TUBB4A 2620/4885TUBB 3292/4885 |
| US-10370349-B2 | Functionalised benzopyran compounds and use thereof | BRCA1, BRAP, EP300 | PTGS1 1785/4885TUBB4A 1400/4885TUBB 1824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.