Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.53 |
| ▸ | CMA1 | P23946 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PRCP | P42785 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8422163 | 1.00 | CTRB1 (0.53) | CTRB1CMA1KMT2AMEN1KLK7 | |
| SCHEMBL11598414 | 0.93 | CTRB1 (0.51) | CTRB1CMA1KMT2AMEN1KLK7 | |
| SCHEMBL31195863 | 0.89 | CTRB1 (0.56) | CTRB1CMA1KMT2AMEN1KLK7 | |
| SCHEMBL30689104 | 0.88 | CMA1 (0.49) | CTRB1CMA1KMT2AMEN1KLK7 | |
| SCHEMBL14174437 | 0.86 | CMA1 (0.48) | CTRB1CMA1KMT2ANPSR1ACE | |
| SCHEMBL30689122 | 0.86 | CTRB1 (0.48) | CTRB1CMA1KMT2AMEN1KLK7 | |
| SCHEMBL11596068 | 0.86 | CTRB1 (0.53) | CTRB1CMA1KMT2AMEN1KLK7 | |
| SCHEMBL29535218 | 0.85 | CTRB1 (0.58) | CTRB1CMA1KMT2AMEN1KLK7 | |
| SCHEMBL7211627 | 0.84 | CTRB1 (0.55) | CTRB1CMA1KMT2AMEN1KLK7 | |
| SCHEMBL27471050 | 0.84 | CTRB1 (0.55) | CTRB1CMA1KMT2AMEN1KLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150224164-A1 | TREATMENT OF AUTISM SPECTRUM DISORDERS USING GLYCYL-L-2-METHYLPROLYL-L-GLUMATIC ACID | NEUREN PHARMACEUTICALS LIMITED (NZ) | 2015-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150224164-A1 | TREATMENT OF AUTISM SPECTRUM DISORDERS USING GLYCYL-L-2-METHYLPROLYL-L-GLUMATIC ACID | GRIN2D, GRM2, GRIK5 | CTRB1 4858/4885CMA1 3445/4885KMT2A 696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.