SCHEMBL17002226

SCHEMBL17002226

Fc1ccc(-c2nc(-c3c(F)cccc3F)[nH]c2-c2ccncc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 15/20 1.00
CSNK1D P48730 5/20 1.00
CSNK1E P49674 4/20 1.00
MAPK13 O15264 12/20 0.74
GCGR P47871 12/20 0.74
MAPK12 P53778 12/20 0.74
MAPK11 Q15759 12/20 0.74
PRKD3 O94806 2/20 0.74
MAP4K4 O95819 2/20 0.74
FRK P42685 2/20 0.74
MAPK9 P45984 2/20 0.74
CSNK1A1 P48729 2/20 0.74
GSK3B P49841 2/20 0.74
PTK6 Q13882 2/20 0.74
CLK4 Q9HAZ1 2/20 0.74
PRKD2 Q9BZL6 1/20 0.74
ALOX5 P09917 5/20 0.71
KDM4E B2RXH2 1/20 0.65
CIT O14578 1/20 0.65
GAK O14976 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17002221 0.92 MAPK14 (0.85) MAPK14CSNK1DCSNK1EMAPK13GCGR
SCHEMBL18960509 0.91 MAPK14 (0.83) MAPK14CSNK1DCSNK1EMAPK13GCGR
SCHEMBL17002177 0.91 MAPK14 (0.83) MAPK14CSNK1DCSNK1EMAPK13GCGR
SCHEMBL17002171 0.91 MAPK14 (0.83) MAPK14CSNK1DCSNK1EMAPK13GCGR
SCHEMBL17002167 0.89 MAPK14 (0.80) MAPK14CSNK1DCSNK1EMAPK13GCGR
SCHEMBL17002222 0.86 MAPK14 (0.76) MAPK14CSNK1DCSNK1EMAPK13GCGR
SCHEMBL17002231 0.86 MAPK14 (0.76) MAPK14CSNK1DCSNK1EMAPK13GCGR
SCHEMBL19868925 0.85 MAPK11 (1.00) MAPK14CSNK1DCSNK1EMAPK13GCGR
SCHEMBL15075603 0.85 MAPK11 (1.00) MAPK14CSNK1DCSNK1EMAPK13GCGR
SCHEMBL30197605 0.85 MAPK14 (1.00) MAPK14CSNK1DCSNK1EMAPK13GCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 387 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137794-A1 LIGAND-DRUG CONJUGATE AND USE THEREOF SYSTIMMUNE INC (US) 2026-05-21 US claimed
EP-4024128-B1 ELECTRONIC DEVICE AND ACCESSORY CANON KK (JP) 2026-05-20 EP claimed
EP-4720261-A1 NOVEL CULTURE CONDITIONS FOR CLONAL EXPANSION OF NEPHRON PROGENITOR CELLS, GENERATION OF NEPHRON ORGANOIDS, AND RAPID AND SCALABLE MODELING OF POLYCYSTIC KIDNEY DISEASE University of Southern California (US) 2026-04-08 EP claimed
EP-4134739-B1 ELECTRONIC DEVICE, AND ACCESSORY CANON KK (JP) 2026-02-11 EP claimed
EP-4615506-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES Sahin, Fikret (TR) 2025-09-17 EP claimed
EP-4527416-A1 LIGAND-DRUG CONJUGATE AND USE THEREOF SystImmune, Inc. (US) 2025-03-26 EP claimed
WO-2024258363-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES SAHIN FIKRET (TR) 2024-12-19 WO claimed
WO-2024243567-A1 NOVEL CULTURE CONDITIONS FOR CLONAL EXPANSION OF NEPHRON PROGENITOR CELLS, GENERATION OF NEPHRON ORGANOIDS, AND RAPID AND SCALABLE MODELING OF POLYCYSTIC KIDNEY DISEASE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2024-11-28 WO claimed
WO-2024234457-A1 KIT AND METHOD FOR CONSTRUCTING HEART ORGANOID FROM PLURIPOTENT STEM CELLS 四川大学华西医院 2024-11-21 WO claimed
WO-2023222019-A9 LIGAND-DRUG CONJUGATE AND USE THEREOF 成都百利多特生物药业有限责任公司 2024-11-14 WO claimed
WO-2023196235-A1 METHODS, DEVICES, AND SYSTEMS FOR TREATING LENS PROTEIN AGGREGATION DISEASES GLAZIER ALAN NEIL (US) 2023-10-12 WO claimed
US-20230310471-A1 METHODS, DEVICES, AND SYSTEMS FOR TREATING LENS PROTEIN AGGREGATION DISEASES GLAZIER ALAN NEIL (US) 2023-10-05 US claimed
CN-116758070-A Method and system for analyzing cells and obtaining morphological characteristics of cells 深圳安侣医学科技有限公司 2023-09-15 CN claimed
CN-116656600-A Kit and method for constructing cardiac organoids by using multifunctional stem cells 四川大学华西医院 2023-08-29 CN claimed
CN-111081402-B Steam generation system suitable for fusion reactor nuclear power station 核工业西南物理研究院 2023-07-14 CN claimed
WO-2023060322-A1 METHODS FOR PRODUCING CARTILAGE AND BONES MURDOCH CHILDREN'S RESEARCH INSTITUTE (AU) 2023-04-20 WO claimed
CN-111081388-B Efficient steam generation system suitable for pulse power reactor 核工业西南物理研究院 2022-11-18 CN claimed
CN-216647182-U Use water supply system's switch board 沈阳华乐世通传动技术有限公司 2022-05-31 CN claimed
CN-112737294-B Method for reducing generation of electric heating resistance-inductance load harmonic waves and current impact 合肥恒力装备有限公司 2022-03-29 CN claimed
CN-111075529-B Brayton cycle power generation system suitable for pulse type fusion reactor 核工业西南物理研究院 2022-02-18 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137794-A1 LIGAND-DRUG CONJUGATE AND USE THEREOF CHEK1, ATR, MRE11 MAPK14 1503/4885CSNK1D 165/4885CSNK1E 129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.