Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 15/20 | 0.65 |
| ▸ | CCNE1 | P24864 | 13/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 13/20 | 0.48 |
| ▸ | CDK7 | P50613 | 12/20 | 0.48 |
| ▸ | CDK4 | P11802 | 9/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 9/20 | 0.48 |
| ▸ | CCND1 | P24385 | 9/20 | 0.48 |
| ▸ | CCNH | P51946 | 9/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 6/20 | 0.46 |
| ▸ | CDK9 | P50750 | 4/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.46 |
| ▸ | CLK2 | P49760 | 2/20 | 0.46 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15387124 | 0.85 | NPSR1 (0.67) | CDK2CCNE1NPSR1MAPK1CDK1 | |
| SCHEMBL19112192 | 0.85 | NPSR1 (0.67) | CDK2CCNE1NPSR1MAPK1CDK1 | |
| SCHEMBL19112178 | 0.85 | NPSR1 (0.67) | CDK2CCNE1NPSR1MAPK1CDK1 | |
| SCHEMBL30356263 | 0.85 | NPSR1 (0.67) | CDK2CCNE1NPSR1MAPK1CDK1 | |
| SCHEMBL23927311 | 0.85 | NPSR1 (0.54) | CDK2CCNE1NPSR1MAPK1MAPT | |
| Hydrochloric Acid SCHEMBL30268945 | 0.84 | NPSR1 (0.66) | CDK2CCNE1NPSR1MAPK1CDK1 | |
| Hydrochloric Acid SCHEMBL23927315 | 0.84 | NPSR1 (0.66) | CDK2CCNE1NPSR1MAPK1CDK1 | |
| Hydrochloric Acid SCHEMBL23927317 | 0.84 | NPSR1 (0.66) | CDK2CCNE1NPSR1MAPK1CDK1 | |
| SCHEMBL22651961 | 0.84 | NPSR1 (0.70) | CDK2CCNE1NPSR1MAPK1MAPT | |
| SCHEMBL17628572 | 0.82 | CDK2 (0.66) | CDK2CCNE1NPSR1MAPK1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10561661-B2 | Purine derivative compounds for medical use | MANROS THERAPEUTICS (FR) | 2020-02-18 | — | — | US | claimed |
| EP-2907514-B1 | Purine derivative compounds for medical use | MANROS THERAPEUTICS (FR) | 2019-10-23 | — | — | EP | claimed |
| US-20150320753-A1 | PURINE DERIVATIVE COMPOUNDS FOR MEDICAL USE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-11-12 | — | — | US | claimed |
| EP-2907514-A1 | Purine derivative compounds for medical use | Manros Therapeutics (FR) | 2015-08-19 | — | — | EP | claimed |
| US-10561661-B2 | Purine derivative compounds for medical use | MANROS THERAPEUTICS (FR) | 2020-02-18 | — | — | US | disclosed |
| EP-2907514-B1 | Purine derivative compounds for medical use | MANROS THERAPEUTICS (FR) | 2019-10-23 | — | — | EP | disclosed |
| US-20150320753-A1 | PURINE DERIVATIVE COMPOUNDS FOR MEDICAL USE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-11-12 | — | — | US | disclosed |
| EP-2907514-A1 | Purine derivative compounds for medical use | Manros Therapeutics (FR) | 2015-08-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150320753-A1 | PURINE DERIVATIVE COMPOUNDS FOR MEDICAL USE | MSR1, TPMT, M6PR | CDK2 2532/4885CCNE1 1270/4885NPSR1 578/4885 |
| US-10561661-B2 | Purine derivative compounds for medical use | MSR1, TPMT, M6PR | CDK2 2532/4885CCNE1 1270/4885NPSR1 578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.