M6PR — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL8615533	0.56	2/20
SCHEMBL15698043	0.56	2/20
SCHEMBL15700171	0.56	2/20
SCHEMBL19502333	0.56	2/20
SCHEMBL20143964	0.56	2/20
SCHEMBL4329591	0.51	2/20
SCHEMBL16093664	0.51	2/20
SCHEMBL16098706	0.51	2/20
SCHEMBL1772063	0.50	2/20
SCHEMBL714447	0.44	2/20
SCHEMBL767063	0.44	2/20
SCHEMBL767128	0.44	2/20
SCHEMBL1004728	0.44	2/20
SCHEMBL1007197	0.44	2/20
SCHEMBL1832193	0.44	2/20
SCHEMBL1919200	0.44	2/20
SCHEMBL2233716	0.44	2/20
SCHEMBL2502348	0.44	2/20
SCHEMBL2505909	0.44	2/20
SCHEMBL2743468	0.44	2/20

Clinical trials — most relevant to M6PR by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Chronic Treatment With Benfotiamine Restores Endothelial Function in People With Type 2 Diabetes Mellitus	PHASE4	UNKNOWN
Trial of Lymphoseek in Intraoperative Localization of Lymph Nodes in Breast Cancer and Melanoma	PHASE3	COMPLETED
D Mannose in Recurrent Urinary Tract Infections	PHASE3	COMPLETED
Diabetic Retinopathy Sulodexide Study	PHASE2	COMPLETED
GM604 Phase 2A Randomized Double-blind Placebo Controlled Pilot Trial in Amyotrophic Lateral Disease (ALS)	PHASE2	COMPLETED
First In Human Safety, Pharmacokinetics and Anti-tumoral Activity of GM102 in Gynecological Cancers	PHASE1	COMPLETED
ERT in Pompe Disease: Elucidation of Molecular Structures Contributing to Enzyme Uptake and Immunoreactivity	nan	UNKNOWN
Clinical Status and Bronchial Inflammation in Patients With Bronchiolitis Obliterans	nan	COMPLETED
Biomarker for Mucolipidosis Disorder Type I, II, III, IV (BioML)	nan	WITHDRAWN
The Natural History of Alpha-Mannosidosis	nan	COMPLETED
International Milk Composition (IMiC) Consortium	nan	ACTIVE_NOT_RECRUITING
Cell Distribution in Induced Sputum in Patients With Asthma	nan	COMPLETED
Glycosylation in Patients With Galactosaemia	nan	COMPLETED
Melanocortin Gene Expression in Lymphocytes of Polymyalgia Patients	nan	COMPLETED
FGL2/Fibroleukin and Hepatitis C Virus Recurrence Post Liver Transplantation	nan	UNKNOWN
Meteorin-like Levels in Individuals With Periodontitis	nan	COMPLETED
Epitranscriptomic Blood Biomarkers for Coronary Artery Disease - A Prospective Cohort Study (IHD-EPITRAN)	nan	UNKNOWN
The Clinical Diagnosis Meaning of MIF in Coronary Heart Disease	nan	COMPLETED
Microbiota in COVID-19 Patients for Future Therapeutic and Preventive Approaches	nan	UNKNOWN
Role of the Inflammatory Receptors in the Pathogenesis of Atherosclerosis	nan	UNKNOWN
Biomarker for Mannosidosis Disease (BioMannosidosis)	nan	WITHDRAWN
Efficacy of an Intravaginal Treatment With Carboxymethyl-β-glucan and Polycarbophil in HR-HPV Clearance	nan	UNKNOWN
Significance of Ficolin 2 in the Determination of Serological Activity in Chronic Inflammatory Bowel Disease	nan	COMPLETED
Institution of an Italian Multicenter Database of Patients Affected by Diseases of Phosphate Metabolism	nan	NOT_YET_RECRUITING
Neutrophils as Prognostic Factors in Granulomatosis With Polyangiitis (Formerly Named Wegener's Granulomatosis)	nan	COMPLETED
Longitudinal Assessment of Marrow and Blood in Patients With Glioblastoma	nan	SUSPENDED
Is in Vitro Maturation of Oocytes Influenced by the Origin of Gonadotropins Used in Maturation Medium: is There a Difference in Efficiency When Using Urinary Versus Recombinant Produced Follicle Stimulating Hormone and Human Chorionic Gonadotropin	nan	UNKNOWN
Predicting Pancreatic Necrosis Using mitDNA	nan	UNKNOWN
Immune Profile and Complication Risk in Type 2 Diabetes	nan	UNKNOWN
Effect of Preoperative Music on Sterile Inflammation Induced by Laparoscopic Surgery	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a M6PR binder may also engage these)

Protein	Name	Similarity
P11456	—	1.000	P11456 →
P24668	—	1.000	P24668 →
Q6AY20	—	0.998	Q6AY20 →
Q5R8S4	—	0.970	Q5R8S4 →
A8WCC4	—	0.970	A8WCC4 →
Q8VEH8	—	0.970	Q8VEH8 →
CSGALNACT1	Chondroitin sulfate N-acetylgalactosaminyltransferase 1	0.967	landscape →
A8MWY0	—	0.967	A8MWY0 →
Q9NRA1	—	0.967	Q9NRA1 →
Q9EQX6	—	0.966	Q9EQX6 →
Q8BJQ9	—	0.966	Q8BJQ9 →
A7E2Z9	—	0.966	A7E2Z9 →
Q3UZV7	—	0.965	Q3UZV7 →
Q8NFZ0	—	0.965	Q8NFZ0 →
Q8R143	—	0.965	Q8R143 →
Q66H91	—	0.964	Q66H91 →
Q8C1F4	—	0.964	Q8C1F4 →
Q6PCX7	—	0.963	Q6PCX7 →
Q0VBD0	—	0.963	Q0VBD0 →
O13097	—	0.963	O13097 →
Q6NRQ1	—	0.962	Q6NRQ1 →
Q9I946	—	0.962	Q9I946 →
Q8CI19	—	0.962	Q8CI19 →
O94985	—	0.962	O94985 →
Q8N6G5	—	0.962	Q8N6G5 →
O73874	—	0.962	O73874 →
O73753	—	0.962	O73753 →
MAP3K20	Mitogen-activated protein kinase kinase kinase 20	0.962	landscape →
D4A6L0	—	0.961	D4A6L0 →
HLCS	Biotin--protein ligase	0.961	landscape →