Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17004313 | 0.83 | CHEK1 (0.30) | — | |
| SCHEMBL17004333 | 0.82 | FLT3 (0.33) | — | |
| SCHEMBL17004203 | 0.81 | SLC6A2 (0.36) | — | |
| SCHEMBL17004331 | 0.81 | CDC7 (0.31) | — | |
| SCHEMBL17004300 | 0.80 | CHEK1 (0.30) | — | |
| SCHEMBL17004270 | 0.80 | PRKDC (0.33) | — | |
| SCHEMBL17004326 | 0.80 | — | — | |
| SCHEMBL17004351 | 0.80 | SLC6A7 (0.36) | — | |
| SCHEMBL17004330 | 0.80 | SLC6A7 (0.36) | — | |
| SCHEMBL17004250 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099795-B1 | AZAADAMANTANE DERIVATIVES AND THEIR USES AS NICOTINIC ACETYLCHOLINE RECEPTORS LIGANDS | ABBVIE BAHAMAS LTD (BS) | 2015-08-19 | — | — | EP | disclosed |