Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 14/20 | 0.53 |
| ▸ | BCL2 | P10415 | 12/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2389444 | 1.00 | BCL2L1 (0.53) | BCL2L1BCL2 | |
| SCHEMBL2389447 | 1.00 | BCL2L1 (0.53) | BCL2L1BCL2 | |
| SCHEMBL2385278 | 0.87 | BCL2 (0.59) | BCL2 | |
| SCHEMBL2384588 | 0.87 | BCL2 (0.59) | BCL2 | |
| SCHEMBL2386142 | 0.81 | BCL2 (0.58) | BCL2 | |
| SCHEMBL2388665 | 0.81 | BCL2 (0.50) | BCL2L1BCL2 | |
| SCHEMBL11973830 | 0.80 | BCL2L1 (0.48) | BCL2L1BCL2 | |
| SCHEMBL11973825 | 0.80 | BCL2L1 (0.48) | BCL2L1BCL2 | |
| SCHEMBL2384577 | 0.80 | BCL2 (0.54) | BCL2L1BCL2 | |
| SCHEMBL17004423 | 0.79 | BCL2 (0.59) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2550258-B1 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBVIE INC (US) | 2015-08-19 | — | — | EP | claimed |