Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 8/20 | 0.46 |
| ▸ | FNTB | P49356 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.37 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL981256 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL982599 | 0.81 | MEN1 (0.47) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL981671 | 0.79 | MEN1 (0.47) | ALDH1A1MEN1KMT2AMAPTSIGMAR1 | |
| SCHEMBL17004382 | 0.79 | ECE2 (0.50) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL979274 | 0.78 | KMT2A (0.45) | ALDH1A1MEN1KMT2AMAPTSIGMAR1 | |
| SCHEMBL979042 | 0.78 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL981878 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL979473 | 0.77 | FNTA (0.49) | FNTAFNTB | |
| SCHEMBL982252 | 0.77 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL980088 | 0.77 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917248-B1 | 1-ACYLDIHYDROPYRAZOL DERIVATIVES | MERCK PATENT GMBH (DE) | 2015-08-19 | — | — | EP | claimed |
| EP-1917248-B1 | 1-ACYLDIHYDROPYRAZOL DERIVATIVES | MERCK PATENT GMBH (DE) | 2015-08-19 | — | — | EP | disclosed |