⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11191472 | 0.75 | — | — | |
| Acetic Acid SCHEMBL7621796 | 0.75 | — | — | |
| SCHEMBL6726899 | 0.75 | — | — | |
| SCHEMBL9877 | 0.75 | — | — | |
| SCHEMBL2875093 | 0.73 | — | — | |
| Dimethylcarbate SCHEMBL15360 | 0.73 | — | — | |
| Dimethylcarbate SCHEMBL1232328 | 0.73 | — | — | |
| SCHEMBL6512198 | 0.72 | — | — | |
| SCHEMBL2708756 | 0.72 | — | — | |
| SCHEMBL6972746 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114981270-A | MLL1 inhibitors and anticancer agents | 诺华公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-102686564-B | Pyrrolidine derivatives | HOFFMANN LA ROCHE | 2014-06-25 | — | — | CN | disclosed |
| EP-2566335-A1 | CONTROLLED RELEASE FROM MACROMOLECULAR CONJUGATES | Prolynx Llc (US) | 2013-03-13 | — | — | EP | disclosed |
| EP-2566334-A1 | CONTROLLED DRUG RELEASE FROM SOLID SUPPORTS | Prolynx Llc (US) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011140393-A1 | CONTROLLED RELEASE FROM MACROMOLECULAR CONJUGATES | PROLYNX LLC (US) | 2011-11-10 | — | — | WO | disclosed |
| WO-2011140392-A1 | CONTROLLED DRUG RELEASE FROM SOLID SUPPORTS | PROLYNX LLC (US) | 2011-11-10 | — | — | WO | disclosed |
| US-20100173935-A1 | Muscarinic Receptor Agonists that are Effective in the Treatment of Pain, Alzheimer's Disease and Schizophrenia | ASTRAZENECA AB (SE) | 2010-07-08 | — | — | US | disclosed |
| CN-101501024-A | Muscarinic receptor agonists that are effective in the treatment of pain, alzheimer's disease and schizophrenia | ASTRAZENECA AB (SE) | 2009-08-05 | — | — | CN | disclosed |
| EP-2035412-A1 | MUSCARINIC RECEPTOR AGONISTS THAT ARE EFFECTIVE IN THE TREATMENT OF PAIN, ALZHEIMER'S DISEASE AND SCHIZOPHRENIA | Astra Zeneca AB (SE) | 2009-03-18 | — | — | EP | disclosed |
| US-20080306069-A1 | Pyrazole Derivatives for the Inhibition of CDK'S and GSK'S | ASTEX THERAPEUTICS LIMITED (UK) | 2008-12-11 | — | — | US | disclosed |
| US-5977089-A | ORALLY ADMINISTERING TENOFOVIR DERIVATIVES | GILEAD SCIENCES, INC. (US) | 1999-11-02 | — | — | US | disclosed |
| US-5922695-A | COMPOUNDS CONTAINING CARBONATE OR CARBAMATE GROUPS | GILEAD SCIENCES, INC. (US) | 1999-07-13 | — | — | US | disclosed |
| EP-0915894-A1 | NUCLEOTIDE ANALOGS | GILEAD SCIENCES, INC. (US) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998004569-A1 | NUCLEOTIDE ANALOGS | GILEAD SCIENCES, INC. (US) | 1998-02-05 | — | — | WO | disclosed |
| EP-0130119-B1 | (ACYLOXYALKOXY) CARBONYL DERIVATIVES AS BIOREVERSIBLE PRODRUG MOIETIES FOR PRIMARY AND SECONDARY AMINE FUNCTIONS IN DRUGS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | MERCK & CO. INC. (US) | 1988-11-09 | — | — | EP | disclosed |
| US-4760057-A | (Acyloxyalkoxy)carbonyl derivatives as bioreversible prodrug moieties for primary and secondary amine functions in drugs | MERCK & CO., INC. (US) | 1988-07-26 | — | — | US | disclosed |
| US-4548929-A | Insecticidal and nematocidal heterobicyclic hydroximinates, thiohydroximidates, and carbamate esters, composition, and method of use thereof | SDS BIOTECH CORPORATION (US) | 1985-10-22 | — | — | US | disclosed |
| EP-0130119-A2 | (Acyloxyalkoxy) carbonyl derivatives as bioreversible prodrug moieties for primary and secondary amine functions in drugs, their preparation and pharmaceutical compositions containing said derivatives | MERCK & CO. INC. (US) | 1985-01-02 | — | — | EP | disclosed |
| US-4479002-A | CHEMICAL INTERMEDIATES FOR INSECTICIDES, PESTICIDES | UNION CARBIDE CORPORATION (US) | 1984-10-23 | — | — | US | disclosed |
| US-4424213-A | PESTICIDES | SDS BIOTECH CORPORATION (US) | 1984-01-03 | — | — | US | disclosed |