⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL572012 | 0.78 | — | — | |
| SCHEMBL15028813 | 0.77 | ALDH1A1 (0.33) | — | |
| SCHEMBL1700484 | 0.75 | — | — | |
| SCHEMBL10614237 | 0.75 | — | — | |
| SCHEMBL11191472 | 0.75 | — | — | |
| SCHEMBL6726899 | 0.75 | — | — | |
| SCHEMBL11471070 | 0.75 | — | — | |
| SCHEMBL10534436 | 0.74 | — | — | |
| SCHEMBL1190178 | 0.73 | — | — | |
| SCHEMBL1925147 | 0.73 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105461708-A | Quinazoline tyrosine kinase inhibitor, and preparation method and application thereof | SHANGHAI SUN-SAIL PHARMACEUTICAL SCIENCE & TECH CO LTD | 2016-04-06 | — | — | CN | claimed |
| US-8426388-B2 | Prodrugs of HIV protease inhibitors | ABBVIE INC. (US) | 2013-04-23 | — | — | US | claimed |
| EP-1773850-B1 | PRODRUGS OF HIV PROTEASE INHIBITORS | ABBOTT LAB (US) | 2013-01-30 | — | — | EP | claimed |
| EP-2336138-A2 | Prodrugs of HIV protease inhibitors | ABBOTT LABORATORIES (US) | 2011-06-22 | — | — | EP | claimed |
| US-20100286032-A1 | PRODRUGS OF HIV PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 2010-11-11 | — | — | US | claimed |
| US-20070270383-A1 | Prodrugs of HIV protease inhibitors | ABBVIE INC. | 2007-11-22 | — | — | US | claimed |
| CN-101023090-A | Prodrugs of HIV protease inhibitors | ABBOTT LAB (US) | 2007-08-22 | — | — | CN | claimed |
| EP-1773850-A2 | PRODRUGS OF HIV PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 2007-04-18 | — | — | EP | claimed |
| WO-2006014282-A2 | PRODRUGS OF HIV PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 2006-02-09 | — | — | WO | claimed |
| CN-119959431-A | Gas chromatography determination method for 2-chloro-N-methylacetamide related substances | 成都奥邦药业有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-103119028-B | 1,2,4-triazolone derivative | TAISHO PHARMACEUTICAL CO.,LTD. (JP) | 2016-05-25 | — | — | CN | disclosed |
| CN-103748074-B | Aryloxy group quinoline derivatives and therapeutical uses thereof | TIANJIN LONGBOGEN PHARMACEUTICAL Co.,Ltd. (CN) | 2016-05-18 | — | — | CN | disclosed |
| CN-104470898-B | Cycloalkyl formic acid analog derivative, its preparation method and in application pharmaceutically | SHANGHAI HENGRUI PHARMACEUTICAL CO.,LTD. (CN) | 2016-04-06 | — | — | CN | disclosed |
| CN-105461708-A | Quinazoline tyrosine kinase inhibitor, and preparation method and application thereof | SHANGHAI SUN-SAIL PHARMACEUTICAL SCIENCE & TECH CO LTD | 2016-04-06 | — | — | CN | disclosed |
| EP-0011370-A1 | Process for preparing 2-chlorosulfinyl-azetidinones | ELI LILLY AND COMPANY (US) | 1980-05-28 | — | — | EP | disclosed |
| US-4165316-A | Process for preparing sulfinyl chlorides from penicillin sulfoxides | ELI LILLY AND COMPANY (US) | 1979-08-21 | — | — | US | disclosed |
| US-4165315-A | CHLORINATION WITH AN N-CHLORO HALOGENATING AGENT | ELI LILLY AND COMPANY (US) | 1979-08-21 | — | — | US | disclosed |
| US-4159272-A | Process for 2-chlorosulfinylazetidin-4-ones | ELI LILLY AND COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4081440-A | Sulfinyl halides and their preparation from penicillin sulfoxides | ELI LILLY AND COMPANY (US) | 1978-03-28 | — | — | US | disclosed |
| US-4075203-A | Process for preparing a 3-exomethylenecepham sulfoxide from penicillin sulfoxides | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |