Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16641783 | 0.92 | KMT2A (0.49) | KMT2ASMN1; SMN2STAT3GAAALDH1A1 | |
| SCHEMBL17316452 | 0.86 | KMT2A (0.40) | KMT2ASMN1; SMN2STAT3GAAALDH1A1 | |
| SCHEMBL18213 | 0.86 | KMT2A (0.54) | KMT2ASMN1; SMN2STAT3GAAALDH1A1 | |
| SCHEMBL3598688 | 0.86 | KMT2A (0.50) | KMT2ASMN1; SMN2STAT3GAAALDH1A1 | |
| SCHEMBL17902 | 0.84 | KMT2A (0.53) | KMT2ASMN1; SMN2STAT3GAAALDH1A1 | |
| SCHEMBL26906068 | 0.84 | STAT3 (0.39) | KMT2ASMN1; SMN2STAT3GAAALDH1A1 | |
| SCHEMBL17386324 | 0.82 | KMT2A (0.42) | KMT2ASMN1; SMN2STAT3GAAALDH1A1 | |
| SCHEMBL10171744 | 0.82 | CYP3A4 (0.48) | KMT2ASMN1; SMN2STAT3GAAALDH1A1 | |
| SCHEMBL17525344 | 0.81 | ALDH1A1 (0.41) | KMT2ASMN1; SMN2ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL21768407 | 0.81 | KMT2A (0.43) | KMT2ASMN1; SMN2STAT3GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025857-A1 | CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2012-03-01 | — | — | WO | disclosed |