SCHEMBL170060

SCHEMBL170060

CC(C)=CC1CC(=O)NC1=O

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAP3K14 Q99558 1/20 0.40
CRBN Q96SW2 1/20 0.38
ALDH1A1 P00352 2/20 0.38
GAA P10253 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CYP19A1 P11511 1/20 0.32
MEN1 O00255 1/20 0.31
APEX1 P27695 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
PRKCG P05129 1/20 0.30
PTPN1 P18031 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylamine SCHEMBL28012597 0.96 MAP3K14 (0.38) MAP3K14CRBNALDH1A1GAAKDM4E
SCHEMBL28109216 0.94 MAP3K14 (0.41) MAP3K14CRBNALDH1A1GAAKDM4E
Boric Acid SCHEMBL2362361 0.94 MAP3K14 (0.36) MAP3K14CRBNALDH1A1GAAKDM4E
Succinimide SCHEMBL28330113 0.93 CRBN (0.39) MAP3K14CRBNALDH1A1GAAKDM4E
SCHEMBL16588789 0.84 ALDH1A1 (0.33) MAP3K14ALDH1A1GAAKDM4EMAPT
Phenol SCHEMBL9486812 0.80 ALDH1A1 (0.38) CRBNALDH1A1GAAKDM4EMAPT
SCHEMBL4993994 0.73 KDM4E (0.33) MAP3K14CRBNALDH1A1GAAKDM4E
SCHEMBL12396073 0.73
SCHEMBL9284439 0.72 MAP3K14 (0.41) MAP3K14CRBNALDH1A1GAAKDM4E
SCHEMBL11060636 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4084 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118339265-A Lubricating oil composition for electric vehicle 雪佛龙日本有限公司 2024-07-12 CN claimed
CN-115975707-B Special oil for ultralow-temperature plateau alpine engine 山东京博新能源控股发展有限公司 2024-07-05 CN claimed
CN-117887187-B Corrosion-resistant power tube and production process thereof 浙江灵通科技股份有限公司 2024-07-02 CN claimed
EP-4388064-A1 FRICTION MODIFIERS WITH IMPROVED FRICTIONAL PROPERTIES AND LUBRICATING COMPOSITIONS CONTAINING THE SAME The Lubrizol Corporation (US) 2024-06-26 EP claimed
CN-118185230-A Wear-resistant polyether-ether-ketone-based composite material and preparation method thereof 江苏君华特种高分子材料股份有限公司 2024-06-14 CN claimed
CN-114450383-B Lubricating composition and method of operating an internal combustion engine 路博润公司 2024-06-11 CN claimed
CN-118146053-A Preparation method of high-molecular polymer sensitized emulsion explosive with low sensitizer content 成远矿业开发股份有限公司 2024-06-07 CN claimed
EP-4377426-A1 1,4-BENZOXAZINE COMPOUNDS AND LUBRICANT COMPOSITIONS CONTAINING THE SAME The Lubrizol Corporation (US) 2024-06-05 EP claimed
EP-3262144-B1 AROMATIC TETRAHEDRAL BORATE COMPOUNDS FOR LUBRICATING COMPOSITIONS LUBRIZOL CORP (US) 2024-05-08 EP claimed
CN-117986472-A Preparation method of stable and controllable micro-screw with high mechanical strength 四川大学 2024-05-07 CN claimed
US-4263152-A OIL ADDITIVES COMPRISING A COMPLEX OF AN ACIDIC MOLYBDENUM COMPOUND, A BASIC NITROGEN-CONTAINING COMPOUND, AND A SULFUR SOURCE; OXIDATION RESISTANCE CHEVRON RESEARCH COMPANY (US) 1981-04-21 US claimed
US-4259194-A Reaction product of ammonium tetrathiomolybdate with basic nitrogen compounds and lubricants containing same CHEVRON RESEARCH COMPANY (US) 1981-03-31 US claimed
EP-0008193-A1 Lubricating composition and method of lubricating a marine diesel engine The British Petroleum Company p.l.c. (GB) 1980-02-20 EP claimed
US-4163729-A LUBRICATING OIL CHEVRON RESEARCH COMPANY (US) 1979-08-07 US claimed
US-4089790-A Synergistic combinations of hydrated potassium borate, antiwear agents, and organic sulfide antioxidants CHEVRON RESEARCH COMPANY (US) 1978-05-16 US claimed
US-4081388-A DISPERSANT, DETERGENT, ANTIRUST, ANTIFOAM OROGIL (FR) 1978-03-28 US claimed
US-4010106-A ALKENYL SUCCINIMIDE, OVERBASED PHENATE, DITHIOPHOSPHATE, CHLORINATED OLEFIN CHEVRON RESEARCH COMPANY (US) 1977-03-01 US claimed
US-4010107-A Corrosion-inhibiting functional fluid CHEVRON RESEARCH COMPANY (US) 1977-03-01 US claimed
US-3997454-A Lubricant containing potassium borate CHEVRON RESEARCH COMPANY (US) 1976-12-14 US claimed
US-3933659-A LUBRICANT, ALKENYL SUCCINIMIDE, DIHYDROCARBYL DITHIOPHOSPHORIC ACID SALT, SULFURIZED PHENATE CHEVRON RESEARCH COMPANY (US) 1976-01-20 US claimed