Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 20/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16767399 | 0.95 | BCL2 (0.85) | BCL2 | |
| SCHEMBL26598937 | 0.95 | BCL2 (0.87) | BCL2 | |
| SCHEMBL2724446 | 0.95 | BCL2 (0.87) | BCL2 | |
| SCHEMBL1700707 | 0.92 | BCL2 (0.85) | BCL2 | |
| SCHEMBL1701710 | 0.92 | BCL2 (1.00) | BCL2 | |
| SCHEMBL31344665 | 0.92 | BCL2 (1.00) | BCL2 | |
| SCHEMBL1700552 | 0.91 | BCL2 (0.85) | BCL2 | |
| SCHEMBL30467971 | 0.88 | BCL2 (1.00) | BCL2 | |
| SCHEMBL1700508 | 0.88 | BCL2 (1.00) | BCL2 | |
| SCHEMBL1700612 | 0.88 | BCL2 (0.88) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2576546-A1 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | Abbvie Inc. (US) | 2013-04-10 | — | — | EP | claimed |
| WO-2011149492-A1 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2011-12-01 | — | — | WO | claimed |