SCHEMBL31344665

SCHEMBL31344665

CC1(C)CCC(CN2CCN(c3ccc(C(=O)NS(=O)(=O)c4ccc(OCC5CCOCC5)c(C#N)c4)c(Oc4cnc5[nH]ccc5c4)c3)CC2)=C(c2ccc(Cl)cc2)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ BCL2 P10415 19/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1701710 1.00 BCL2 (1.00) BCL2
SCHEMBL1701804 0.94 BCL2 (1.00) BCL2
SCHEMBL1702328 0.93 BCL2 (1.00) BCL2
SCHEMBL30313940 0.93 BCL2 (1.00) BCL2
SCHEMBL19419658 0.93 BCL2 (0.87) BCL2
SCHEMBL29657510 0.93 BCL2 (1.00) BCL2
SCHEMBL1700205 0.93 BCL2 (1.00) BCL2
SCHEMBL30313993 0.92 BCL2 (0.91) BCL2
SCHEMBL1701413 0.92 BCL2 (0.91) BCL2
SCHEMBL1700615 0.92 BCL2 (0.85) BCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4682148-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2026-01-21 — — EP disclosed
EP-4474383-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2024-12-11 — — EP disclosed
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