SCHEMBL17006292

SCHEMBL17006292

O=C(O)c1ccc2c(c1)C(=O)OC2=O.O=C(O)c1ccc2c(c1)C(=O)OC2=O.Oc1ccc(C2(c3ccc(O)cc3-c3ccccc3)c3ccccc3-c3ccccc32)c(-c2ccccc2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 4/20 0.44
CA12 O43570 4/20 0.44
CA7 P43166 4/20 0.44
CA1 P00915 3/20 0.44
CA4 P22748 2/20 0.44
TTR P02766 2/20 0.43
ALDH1A1 P00352 1/20 0.43
PTPRC P08575 2/20 0.42
KMT2A Q03164 2/20 0.40
POLB P06746 1/20 0.40
CA2 P00918 2/20 0.39
CA9 Q16790 1/20 0.39
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
CYP2C19 P33261 1/20 0.38
HTT P42858 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38
SMAD3 P84022 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17006294 0.87 POLB (0.48) PDK2CA12CA7CA1CA4
SCHEMBL17006299 0.85 PDK2 (0.42) PDK2CA12CA7CA1CA4
SCHEMBL17006302 0.84 PDK2 (0.44) PDK2CA12CA7CA1CA4
SCHEMBL15754326 0.84 CA12 (0.46) PDK2CA12CA7CA1CA4
SCHEMBL17006290 0.83 PDK2 (0.40) PDK2CA12CA7CA1CA4
SCHEMBL17006291 0.82 ESR1 (0.43) PDK2CA12CA7CA1CA4
SCHEMBL17006288 0.81 PDK2 (0.38) PDK2CA12CA7CA1CA4
SCHEMBL3446444 0.79 PDK2 (0.53) PDK2ALDH1A1KMT2AMEN1MAPT
SCHEMBL29824042 0.78 PDK2 (0.49) PDK2CA12CA7CA1CA4
SCHEMBL28874569 0.78 PDK2 (0.49) PDK2CA12CA7CA1CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150232665-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT HAVING THEREOF CHI MEI CORPORATION (TW) 2015-08-20 US disclosed