SCHEMBL17006291

SCHEMBL17006291

O=C(O)c1ccc2c(c1)C(=O)OC2=O.O=C(O)c1ccc2c(c1)C(=O)OC2=O.Oc1ccc(C2(c3ccc(O)c(-c4ccccc4)c3)c3ccccc3-c3ccccc32)cc1-c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.43
ESR2 Q92731 1/20 0.43
ALDH1A1 P00352 2/20 0.41
TTR P02766 2/20 0.41
GAA P10253 1/20 0.41
PKM P14618 1/20 0.41
PDK2 Q15119 3/20 0.40
PTPRC P08575 2/20 0.40
CA12 O43570 4/20 0.40
CA7 P43166 4/20 0.40
CA1 P00915 3/20 0.40
CA4 P22748 2/20 0.40
POLB P06746 1/20 0.39
KMT2A Q03164 1/20 0.39
SRD5A2 P31213 1/20 0.36
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
TDP2 O95551 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17006300 0.87 ESR1 (0.62) ESR1ESR2ALDH1A1TTRGAA
SCHEMBL15754326 0.85 CA12 (0.46) ESR1ESR2ALDH1A1TTRGAA
SCHEMBL17006298 0.85 ESR1 (0.44) ESR1ESR2TTRGAAPKM
SCHEMBL17006289 0.84 ESR1 (0.43) ESR1ESR2TTRGAAPKM
SCHEMBL17006301 0.82 ESR1 (0.42) ESR1ESR2TTRGAAPKM
SCHEMBL17006292 0.82 PDK2 (0.44) ALDH1A1TTRGAAPKMPDK2
SCHEMBL17006293 0.81 ESR1 (0.40) ESR1ESR2TTRGAAPKM
SCHEMBL29837106 0.80 ESR1 (0.63) ESR1ESR2ALDH1A1GAAPDK2
SCHEMBL218750 0.80 ESR1 (0.63) ESR1ESR2ALDH1A1GAAPDK2
SCHEMBL29389637 0.80 ESR1 (0.63) ESR1ESR2ALDH1A1GAAPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150232665-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT HAVING THEREOF CHI MEI CORPORATION (TW) 2015-08-20 US disclosed