SCHEMBL1700658

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1700210	0.88	LRRK2 (0.37)	LRRK2BCL2
	SCHEMBL1700050	0.88	LRRK2 (0.33)	LRRK2CA2CA1CA12CA9
	SCHEMBL1700371	0.87	BCL2 (0.37)	LRRK2BCL2CA2CA1CA12
	SCHEMBL1700293	0.85	BCL2 (0.35)	LRRK2BCL2CA2CA1CA12
	SCHEMBL1958508	0.85	BCL2 (0.36)	LRRK2BCL2CA2CA1CA12
	SCHEMBL1700768	0.82	CA2 (0.36)	BCL2CA2CA1CA12CA9
	SCHEMBL1700646	0.79	AKT1 (0.34)	BCL2CA2CA1CA12CA9
	SCHEMBL1700529	0.78	LRRK2 (0.40)	LRRK2
	SCHEMBL1700261	0.78	CA2 (0.47)	CA2
	SCHEMBL1700258	0.78	CA1 (0.37)	CA2CA1CA12CA9CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.