Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.87 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL23931526 | 1.00 | ALDH1A1 (0.87) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| Hydrogen Peroxide SCHEMBL29009637 | 0.97 | ALDH1A1 (0.93) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| Bicarbonate SCHEMBL3469493 | 0.94 | ALDH1A1 (0.77) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL3673 | 0.93 | — | — | |
| SCHEMBL1332089 | 0.93 | — | — | |
| SCHEMBL1958756 | 0.93 | ALDH1A1 (1.00) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| Bicarbonate SCHEMBL23051690 | 0.91 | ALDH1A1 (0.72) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| Bicarbonate SCHEMBL28256793 | 0.91 | ALDH1A1 (0.72) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| Benzene SCHEMBL27658560 | 0.90 | ALDH1A1 (0.81) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| Acetic Acid SCHEMBL440573 | 0.90 | ALDH1A1 (0.81) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1500 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118336122-A | Electrolyte and sodium ion battery for stabilizing lamellar positive electrode by synergistic action of nitrile cosolvent and double salts | 河北工业大学 | 2024-07-12 | — | — | CN | claimed |
| CN-118016844-A | Preparation method and application of nitrogen-doped bamboo charcoal packaged micron-sized silicon anode material | 河北工业大学 | 2024-05-10 | — | — | CN | claimed |
| CN-117936751-A | Potassium-based layered oxide positive electrode material and preparation method and application thereof | 西安交通大学 | 2024-04-26 | — | — | CN | claimed |
| CN-116885121-A | Nickel-crosslinked sodium alginate-induced vanadium sodium phosphate composite positive electrode material, and preparation method and application thereof | 中北大学 | 2023-10-13 | — | — | CN | claimed |
| CN-116864673-A | Polyimide in-situ composite porous sodium vanadium phosphate positive electrode material, and preparation method and application thereof | 中北大学 | 2023-10-10 | — | — | CN | claimed |
| CN-116417683-A | Double-bond-regulated cellulose-based gel polymer electrolyte and preparation method thereof | 华南理工大学 | 2023-07-11 | — | — | CN | claimed |
| CN-116315093-A | Electrolyte additive, application method thereof and battery containing additive | 深圳大学 | 2023-06-23 | — | — | CN | claimed |
| EP-3607601-B1 | LITHIUM SALT MIXTURE AND USES THEREOF AS A BATTERY ELECTROLYTE | ARKEMA FRANCE (FR) | 2023-05-03 | — | — | EP | claimed |
| CN-115117457-B | Preparation method of potassium ion full-cell device | 河南师范大学 | 2023-04-25 | — | — | CN | claimed |
| CN-115588732-A | Preparation method and application of carbon nanotube composite cathode embedded with hollow aluminum nanoparticles in situ | 桂林理工大学 | 2023-01-10 | — | — | CN | claimed |
| EP-1948587-A2 | PROCESS FOR MAKING DIARYL CARBONATE | Catalytic Distillation Technologies (US) | 2008-07-30 | — | — | EP | claimed |
| US-7288668-B2 | Process for making diaryl carbonate | CATALYTIC DISTILLATION TECHNOLOGIES (US) | 2007-10-30 | — | — | US | claimed |
| WO-2007061480-A2 | PROCESS FOR MAKING DIARYL CARBONATE | CATALYTIC DISTILLATION TECHNOLOGIES (US) | 2007-05-31 | — | — | WO | claimed |
| US-20070112214-A1 | Process for making diaryl carbonate | CATALYTIC DISTILLATION TECHNOLOGIES | 2007-05-17 | — | — | US | claimed |
| CN-1259360-C | Polymer gel factor and its constructed molecular gel electrolyte | UNIV HUAZHONG SCIENCE TECH (CN) | 2006-06-14 | — | — | CN | claimed |
| CN-1597743-A | Polymer gel factor and its constructed molecular gel electrolyte | HUAZHONG TECHNOLOGY UNIV (CN) | 2005-03-23 | — | — | CN | claimed |
| US-6770397-B1 | REPETITION OF CHARGE-DISCHARGE CYCLE; OPTIONALLY CROSSLINKED (METH)ACRYLATE POLYMER | ZEON CORPORATION (JP) | 2004-08-03 | — | — | US | claimed |
| EP-0704921-B1 | Nonaqueous secondary battery | UBE INDUSTRIES (JP) | 2003-07-16 | — | — | EP | claimed |
| US-5683834-A | SHEET ELECTRODES WITH COLLECTORS COATED AND LITHIUM SALT ELECTROLYTES | FUJI PHOTO FILM CO., LTD. (JP) | 1997-11-04 | — | — | US | claimed |
| EP-0704921-A1 | Nonaqueous secondary battery | FUJI PHOTO FILM CO., LTD. (JP) | 1996-04-03 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112214-A1 | Process for making diaryl carbonate | AGL, DDT, DAGLA | ALDH1A1 4367/4885SOAT1 2874/4885LMNA 2382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.