Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18279737 | 0.89 | CPB1 (0.42) | TSHRFFAR4 | |
| SCHEMBL17008624 | 0.86 | FFAR4 (0.43) | FFAR4 | |
| SCHEMBL18279743 | 0.86 | FFAR4 (0.43) | FFAR4 | |
| SCHEMBL5925105 | 0.81 | CA1 (0.49) | PKMMAPTNPSR1TSHRFFAR4 | |
| SCHEMBL18630954 | 0.81 | CA1 (0.49) | PKMMAPTNPSR1TSHRFFAR4 | |
| SCHEMBL23970385 | 0.81 | CA1 (0.49) | PKMMAPTNPSR1TSHRFFAR4 | |
| SCHEMBL15927893 | 0.81 | CA1 (0.49) | PKMMAPTNPSR1TSHRFFAR4 | |
| SCHEMBL5453543 | 0.81 | CA1 (0.49) | PKMMAPTNPSR1TSHRFFAR4 | |
| SCHEMBL23970542 | 0.81 | CA1 (0.49) | PKMMAPTNPSR1TSHRFFAR4 | |
| SCHEMBL15927903 | 0.81 | CA1 (0.49) | PKMMAPTNPSR1TSHRFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015120580-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2015-08-20 | — | — | WO | disclosed |