Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 3/20 | 0.43 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8827475 | 0.91 | CES1 (0.43) | SSTR4SSTR1CES1HDAC1HDAC2 | |
| SCHEMBL17674534 | 0.86 | SSTR4 (0.43) | SSTR4SSTR1CES1HDAC1HDAC2 | |
| SCHEMBL1557506 | 0.83 | SSTR4 (0.41) | SSTR4SSTR1CES1HDAC1HDAC2 | |
| SCHEMBL1170319 | 0.83 | PARP10 (0.42) | SSTR4SSTR1CES1HDAC1HDAC2 | |
| SCHEMBL1170317 | 0.83 | SSTR4 (0.41) | SSTR4SSTR1CES1HDAC1HDAC2 | |
| SCHEMBL25353899 | 0.81 | SSTR4 (0.40) | SSTR4SSTR1CES1HDAC1HDAC2 | |
| SCHEMBL17491573 | 0.79 | SSTR4 (0.38) | SSTR4SSTR1CES1HDAC1HDAC2 | |
| SCHEMBL20387981 | 0.78 | SSTR4 (0.50) | SSTR4SSTR1EPHX2CYP1A2CYP2C19 | |
| SCHEMBL27976153 | 0.77 | EPHX2 (0.52) | HDAC1HDAC2SERPINE1EPHX2CYP1A2 | |
| Acetic Acid SCHEMBL29103732 | 0.76 | EPHX2 (0.50) | HDAC1HDAC2SERPINE1EPHX2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240115649-A1 | CASPASE INHIBITION TO ENHANCE REGENERATION AND REPAIR AFTER SKIN OR GUT INJURY AND TO TREAT BACTERIAL OR VIRAL INFECTIONS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-04-11 | — | — | US | claimed |
| EP-4531919-A1 | METHOD OF TREATING VITILIGO WITH INTERFERON-GAMMA ANTIBODY | Elixiron Immunotherapeutics (Hong Kong) Limited (HK) | 2025-04-09 | — | — | EP | disclosed |
| WO-2023235830-A1 | METHOD OF TREATING VITILIGO WITH INTERFERON-GAMMA ANTIBODY | ELIXIRON IMMUNOTHERAPEUTICS (HONG KONG) (CN) | 2023-12-07 | — | — | WO | disclosed |
| EP-3049530-B1 | METHOD FOR CELL-FREE PROTEIN SYNTHESIS IN THE PRESENCE OF A CASPASE INHIBITOR | FRAUNHOFER GES FORSCHUNG (DE) | 2022-06-22 | — | — | EP | disclosed |
| CN-109072193-A | The composition and method of B cell genome editor | 达纳-法伯癌症研究所有限公司 | 2018-12-21 | — | — | CN | disclosed |
| US-9951366-B2 | Cell-free protein synthesis method and device using a eukaryotic cell lysate in the presence of a caspase inhibitor and the use of a caspase inhibitor for increasing the yield and/or the stability of the synthesized proteins in such a method | FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E. V. (DE) | 2018-04-24 | — | — | US | disclosed |
| CN-106232106-A | Particulate vaccine formulations for inducing innate and adaptive immunity | 奥本大学 | 2016-12-14 | — | — | CN | disclosed |
| US-20160251692-A1 | CELL-FREE PROTEIN SYNTHESIS METHOD AND DEVICE USING A EUKARYOTIC CELL LYSATE IN THE PRESENCE OF A CASPASE INHIBITOR AND THE USE OF A CASPASE INHIBITOR FOR INCREASING THE YIELD AND/OR THE STABILITY OF THE SYNTHESIZED PROTEINS IN SUCH A METHOD | FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E. V. (DE) | 2016-09-01 | — | — | US | disclosed |
| WO-2011137485-A1 | MEDIA AND METHODS FOR CELL CULTURE | SYDNEY IVF LIMITED (AU) | 2011-11-10 | — | — | WO | disclosed |
| EP-0840614-A1 | CALPAIN INHIBITORS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | SANOFI WINTHROP, INC. (US) | 1998-05-13 | — | — | EP | disclosed |
| WO-1996041638-A1 | CALPAIN INHIBITORS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | SANOFI WINTHROP, INC. (US) | 1996-12-27 | — | — | WO | disclosed |