Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL29103732 | 0.89 | EPHX2 (0.50) | EPHX2CYP1A2CYP2C19LTA4HKMT2A | |
| SCHEMBL168125 | 0.88 | KIF11 (0.47) | EPHX2CYP1A2CYP2C19LTA4HKMT2A | |
| SCHEMBL27862141 | 0.88 | KIF11 (0.47) | EPHX2CYP1A2CYP2C19LTA4HKMT2A | |
| Methyl Alcohol SCHEMBL27964960 | 0.86 | CCR6 (0.47) | EPHX2CYP1A2CYP2C19LTA4HKMT2A | |
| Fluoride SCHEMBL28371495 | 0.85 | KIF11 (0.46) | EPHX2CYP1A2CYP2C19LTA4HKMT2A | |
| SCHEMBL4036809 | 0.85 | KIF11 (0.46) | EPHX2CYP1A2CYP2C19LTA4HKMT2A | |
| SCHEMBL29087324 | 0.85 | KIF11 (0.46) | EPHX2CYP1A2CYP2C19LTA4HKMT2A | |
| Ammonia Solution, Strong SCHEMBL2163079 | 0.85 | KIF11 (0.46) | EPHX2CYP1A2CYP2C19LTA4HKMT2A | |
| Hydrogen Sulfide SCHEMBL27539287 | 0.85 | KIF11 (0.46) | EPHX2CYP1A2CYP2C19LTA4HKMT2A | |
| Water SCHEMBL27610464 | 0.85 | KIF11 (0.46) | EPHX2CYP1A2CYP2C19LTA4HKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102365020-B | Pyridazinone compounds | TAKEDA PHARMACEUTICAL | 2014-07-30 | — | — | CN | disclosed |