Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.52 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30303130 | 1.00 | HSP90AA1 (0.52) | HSP90AA1HSP90AB1CDK8CDK19KDM4E | |
| SCHEMBL21603492 | 0.83 | HSP90AA1 (0.52) | HSP90AA1HSP90AB1CDK8CDK19KDM4E | |
| SCHEMBL21865977 | 0.83 | HSP90AA1 (0.52) | HSP90AA1HSP90AB1CDK8CDK19KDM4E | |
| SCHEMBL30054247 | 0.80 | HSP90AA1 (0.48) | HSP90AA1HSP90AB1CDK8CDK19KDM4E | |
| SCHEMBL19711936 | 0.80 | HSP90AA1 (0.48) | HSP90AA1HSP90AB1CDK8CDK19KDM4E | |
| SCHEMBL18299983 | 0.80 | HSP90AA1 (0.48) | HSP90AA1HSP90AB1CDK8CDK19KDM4E | |
| SCHEMBL18299583 | 0.80 | HSP90AA1 (0.48) | HSP90AA1HSP90AB1CDK8CDK19KDM4E | |
| SCHEMBL3062694 | 0.75 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1CDK8CDK19KDM4E | |
| SCHEMBL16543893 | 0.74 | CDK8 (0.46) | HSP90AA1HSP90AB1CDK8CDK19KDM4E | |
| SCHEMBL29626748 | 0.72 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1KDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107912-B1 | DERIVATIVES OF 2-(HET)ARYL-SUBSTITUTED CONDENSED BICYCLIC HETEROCYCLES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2024-07-10 | — | — | EP | disclosed |
| EP-3864015-B1 | PROCESS FOR THE PREPARATION OF IMIDAZOLE DERIVATEIVES | BAYER AG (DE) | 2023-05-10 | — | — | EP | disclosed |
| CN-112867713-B | Process for preparing imidazole derivatives | 拜耳公司 | 2023-05-05 | — | — | CN | disclosed |
| US-20230087882-A1 | 2-(Het)aryl-substituted fused bicyclic heterocycle derivatives as pesticides | BAYER CROPSCIENCE AG (DE) | 2023-03-23 | — | — | US | disclosed |
| CN-110312718-B | Heterocyclene derivatives as pest control agents | 拜耳公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-110062756-B | 2- (hetero) aryl-substituted fused bicyclic heterocyclic derivatives as pest control agents | 拜耳作物科学股份公司 | 2022-09-02 | — | — | CN | disclosed |
| US-11339155-B2 | 2-(het)aryl-substituted fused bicyclic heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2022-05-24 | — | — | US | disclosed |
| CN-110382485-B | Heterocyclene derivatives as pest control agents | 拜耳公司 | 2022-05-10 | — | — | CN | disclosed |
| US-11274097-B2 | 2-(het)aryl-substituted condensed bicyclic heterocycle derivatives as pest control agents | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2022-03-15 | — | — | US | disclosed |
| US-20220009930-A1 | PROCESS FOR PREPARING IMIDAZOLE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2022-01-13 | — | — | US | disclosed |
| CN-107207506-A | Condensed heterocyclic compouds and noxious organism control agent | 日产化学工业株式会社 | 2017-09-26 | — | — | CN | disclosed |
| WO-2017121674-A1 | HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-07-20 | — | — | WO | disclosed |
| WO-2017072039-A1 | CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-05-04 | — | — | WO | disclosed |
| US-20170073342-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-03-16 | — | — | US | disclosed |
| EP-3107912-A1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2016-12-28 | — | — | EP | disclosed |
| WO-2016169886-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYLES | SYNGENTA CROP PROTECTION AG (CH) | 2016-10-27 | — | — | WO | disclosed |
| WO-2016162318-A1 | CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS AND INTERMEDIATE PRODUCT | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-10-13 | — | — | WO | disclosed |
| WO-2016124557-A1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-08-11 | — | — | WO | disclosed |
| WO-2016124563-A1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHSAFT (DE) | 2016-08-11 | — | — | WO | disclosed |
| WO-2015121136-A1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2015-08-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11274097-B2 | 2-(het)aryl-substituted condensed bicyclic heterocycle derivatives as pest control agents | CYP8B1, CYP4B1, CYP1B1 | HSP90AA1 563/4885HSP90AB1 751/4885CDK8 2246/4885 |
| US-20230087882-A1 | 2-(Het)aryl-substituted fused bicyclic heterocycle derivatives as pesticides | CYP1B1, CYP4B1, CYP8B1 | HSP90AA1 1594/4885HSP90AB1 1640/4885CDK8 3845/4885 |
| US-20170073342-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | CYP1B1, CYP4B1, CYP8B1 | HSP90AA1 1475/4885HSP90AB1 1560/4885CDK8 3788/4885 |
| US-11339155-B2 | 2-(het)aryl-substituted fused bicyclic heterocycle derivatives as pesticides | EPHX2, CYP8B1, CYP1B1 | HSP90AA1 2670/4885HSP90AB1 3227/4885CDK8 3251/4885 |
| US-20220009930-A1 | PROCESS FOR PREPARING IMIDAZOLE DERIVATIVES | UQCRB, CYP3A4, H1-4 | HSP90AA1 3978/4885HSP90AB1 3755/4885CDK8 525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.