SCHEMBL17009062

SCHEMBL17009062

CC(N)(C=O)C=Cc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.59
ALDH1A1 P00352 3/20 0.43
LMNA P02545 2/20 0.43
TRPA1 O75762 1/20 0.43
ALOX5 P09917 1/20 0.43
MAPK1 P28482 1/20 0.43
NPC1 O15118 2/20 0.41
TSHR P16473 1/20 0.41
EGFR P00533 1/20 0.41
GLA P06280 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MAOB P27338 2/20 0.39
CYP2A6 P11509 1/20 0.39
CYP19A1 P11511 1/20 0.39
MAOA P21397 1/20 0.39
HDAC1 Q13547 2/20 0.38
HDAC3 O15379 1/20 0.38
TNKS O95271 1/20 0.38
HDAC4 P56524 1/20 0.38
HCAR2 Q8TDS4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9425926 0.79 CYP2C19 (0.62) CYP2C19ALDH1A1TRPA1NPC1TSHR
SCHEMBL3258195 0.79 CYP2C19 (0.62) CYP2C19ALDH1A1TRPA1NPC1TSHR
SCHEMBL9634579 0.74 CYP2C19 (0.49) CYP2C19ALDH1A1LMNATRPA1ALOX5
SCHEMBL6286942 0.73 CYP2C19 (0.55) CYP2C19ALDH1A1LMNATRPA1ALOX5
SCHEMBL28939716 0.73 CYP2C19 (0.55) CYP2C19ALDH1A1LMNATRPA1ALOX5
SCHEMBL26917 0.73 CYP2C19 (0.55) CYP2C19ALDH1A1LMNATRPA1ALOX5
SCHEMBL3259240 0.73 CYP2C19 (0.55) CYP2C19ALDH1A1LMNATRPA1ALOX5
Benzene SCHEMBL27345987 0.73 CYP2C19 (0.55) CYP2C19ALDH1A1LMNATRPA1ALOX5
SCHEMBL5664878 0.72 CYP2C19 (0.53) CYP2C19ALDH1A1LMNATRPA1ALOX5
Water SCHEMBL15415928 0.72 CYP2C19 (0.53) CYP2C19ALDH1A1LMNATRPA1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109071422-A The regulator that linear and false ring extension for controlling vinyl monomer polymerize 迪斯普泰科有限公司 2018-12-21 CN disclosed
EP-3105280-A1 SULFUR COMPOSITES AND POLYMERIC MATERIALS FROM ELEMENTAL SULFUR The Arizona Board of Regents for and on behalf of Arizona State University (US) 2016-12-21 EP disclosed
WO-2015123552-A1 SULFUR COMPOSITES AND POLYMERIC MATERIALS FROM ELEMENTAL SULFUR THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2015-08-20 WO disclosed