Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | CHAT | P28329 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3259240 | 1.00 | CYP2C19 (0.55) | CYP2C19MAOBCHATEGFRALDH1A1 | |
| SCHEMBL28939716 | 1.00 | CYP2C19 (0.55) | CYP2C19MAOBCHATEGFRALDH1A1 | |
| SCHEMBL26917 | 1.00 | CYP2C19 (0.55) | CYP2C19MAOBCHATEGFRALDH1A1 | |
| SCHEMBL29171014 | 0.97 | CYP2C19 (0.53) | CYP2C19MAOBCHATEGFRALDH1A1 | |
| Water SCHEMBL15415928 | 0.97 | CYP2C19 (0.53) | CYP2C19MAOBCHATEGFRALDH1A1 | |
| Ethylene SCHEMBL17997367 | 0.95 | CYP2C19 (0.52) | CYP2C19MAOBCHATEGFRALDH1A1 | |
| Butadiene SCHEMBL7155720 | 0.93 | CYP2C19 (0.50) | CYP2C19MAOBCHATEGFRALDH1A1 | |
| SCHEMBL3713678 | 0.91 | CYP2C19 (0.48) | CYP2C19MAOBCHATEGFRALDH1A1 | |
| O-Xylene SCHEMBL10337916 | 0.91 | CYP2C19 (0.48) | CYP2C19MAOBCHATEGFRALDH1A1 | |
| Styrene SCHEMBL3804814 | 0.91 | ALDH1A1 (0.61) | CYP2C19MAOBCHATEGFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535286-A | Gem-difluoro cyclopentene compound and preparation method thereof | 四川大学 | 2023-08-04 | — | — | CN | disclosed |
| US-11124643-B2 | Thermoplastic resin composition and molded article manufactured therefrom | LOTTE CHEMICAL CORPORATION (KR) | 2021-09-21 | — | — | US | disclosed |
| CN-109761810-B | Preparation method of inactive alkene aryl compound | 浙江工业大学 | 2021-07-27 | — | — | CN | disclosed |
| EP-3774389-A1 | TYRE COMPRISING A RUBBER COMPOSITION COMPRISING A NOVEL POLYSULPHIDE COUPLING AGENT BEARING NITROGEN-CONTAINING ASSOCIATIVE GROUPS | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2021-02-17 | — | — | EP | disclosed |
| US-20200079951-A1 | Thermoplastic Resin Composition and Molded Article Manufactured Therefrom | LOTTE CHEMICAL CORPORATION (KR) | 2020-03-12 | — | — | US | disclosed |
| WO-2019193286-A1 | TYRE COMPRISING A RUBBER COMPOSITION COMPRISING A NOVEL POLYSULPHIDE COUPLING AGENT BEARING NITROGEN-CONTAINING ASSOCIATIVE GROUPS | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2019-10-10 | — | — | WO | disclosed |
| CN-109761810-A | A kind of preparation method of torpescence alkene aryl compound | 浙江工业大学 | 2019-05-17 | — | — | CN | disclosed |
| US-20150191607-A1 | Anti-fouling Paints and Coatings | REACTIVE SURFACES, LTD (US) | 2015-07-09 | — | — | US | disclosed |
| US-20150023921-A1 | HEPATITIS C ANTIVIRAL COMPOSITIONS AND METHODS | BIOTRON LIMITED (AU) | 2015-01-22 | — | — | US | disclosed |
| US-8669280-B2 | Antiviral compounds and methods | BIOTRON LIMITED (AU) | 2014-03-11 | — | — | US | disclosed |
| US-6900273-B1 | Low-hygroscopicity low-birefringence resin compositions, molding material obtained therefrom, sheet or film, and optical part | HITACHI CHEMICAL CO., LTD. (JP) | 2005-05-31 | — | — | US | disclosed |
| US-20040220342-A1 | Low-hygroscopicity low-birefringence resin compositions, molding material, sheet or film obtained therefrom, and optical part | YAMASHITA YUKIHIKO (JP) | 2004-11-04 | — | — | US | disclosed |
| EP-1205517-A1 | LOW-HYGROSCOPICITY LOW-BIREFRINGENCE RESIN COMPOSITIONS, MOLDING MATERIAL OBTAINED THEREFROM, SHEET OR FILM, AND OPTICAL PART | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2002-05-15 | — | — | EP | disclosed |
| US-3992472-A | Synthesis of ethylenically unsaturated compounds from aldehydes or ketones | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-11-16 | — | — | US | disclosed |
| US-3988332-A | Hydrocarbylidene compounds of niobium and tantalum | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150023921-A1 | HEPATITIS C ANTIVIRAL COMPOSITIONS AND METHODS | HAVCR2, HCCS, EIF2AK2 | CYP2C19 4095/4885MAOB 883/4885CHAT 2462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.