Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12935681 | 0.81 | PRMT1 (0.48) | PRMT1ECE1LTA4HADRA1ALMNA | |
| SCHEMBL3130249 | 0.79 | PAOX (0.52) | SLC22A6ALDH1A1TSHRS1PR1S1PR3 | |
| SCHEMBL2804324 | 0.79 | PRMT1 (0.52) | PRMT1LTA4HADRA1ALMNASLC22A6 | |
| SCHEMBL30407212 | 0.79 | PRMT1 (0.46) | PRMT1ECE1LTA4HADRA1ALMNA | |
| SCHEMBL4941181 | 0.79 | — | — | |
| SCHEMBL39829 | 0.77 | TSHR (0.63) | PRMT1ADRA1ALMNASLC22A6ALDH1A1 | |
| SCHEMBL6902609 | 0.77 | TSHR (0.63) | PRMT1ADRA1ALMNASLC22A6ALDH1A1 | |
| SCHEMBL20518454 | 0.77 | TSHR (0.63) | PRMT1ADRA1ALMNASLC22A6ALDH1A1 | |
| SCHEMBL6900773 | 0.77 | TSHR (0.63) | PRMT1ADRA1ALMNASLC22A6ALDH1A1 | |
| SCHEMBL6899587 | 0.77 | TSHR (0.63) | PRMT1ADRA1ALMNASLC22A6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3104867-A1 | COMPOSITIONS AND METHODS TO IMPROVE THE HOMING AND GRAFTING OF HEMATOPOETIC STEM CELLS | 7 HILLS INTERESTS, LLC (US) | 2016-12-21 | — | — | EP | disclosed |
| WO-2015123447-A1 | COMPOSITIONS AND METHODS TO IMPROVE THE HOMING AND GRAFTING OF HEMATOPOETIC STEM CELLS | 7 HILLS PHARMA, LLC (US) | 2015-08-20 | — | — | WO | disclosed |