Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.63 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | PPARD | Q03181 | 6/20 | 0.50 |
| ▸ | PPARA | Q07869 | 6/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7100034 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22PRMT1 | |
| SCHEMBL20518454 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22PRMT1 | |
| SCHEMBL6899587 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22PRMT1 | |
| SCHEMBL6900773 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22PRMT1 | |
| SCHEMBL39829 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22PRMT1 | |
| SCHEMBL4941181 | 0.97 | — | — | |
| 4-(Hydroxyamino)Butanoic Acid SCHEMBL1655977 | 0.89 | — | — | |
| 4-(Hydroxyamino)Butanoic Acid SCHEMBL28266183 | 0.86 | — | — | |
| SCHEMBL25409488 | 0.81 | TSHR (0.67) | TSHRLMNANFKB1PMP22PRMT1 | |
| SCHEMBL13657827 | 0.81 | TSHR (0.67) | TSHRLMNANFKB1PMP22PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110729-A1 | Primary N-hydroxylamines | NIH | 2004-06-10 | — | — | US | claimed |
| US-6455589-B1 | AN ORALLY ADMINISTRABLE EFFECTIVE UNIT SOLID DOSAGE OF A PRIMARY N-HYDROXYLAMINE OR A SALT, FREE OF NITRONE; USEFUL FOR REDUCING OXIDATIVE DAMAGE OR DELAYING SENESCENCE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-09-24 | — | — | US | claimed |