Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | HTT | P42858 | 5/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TOP2A | P11388 | 2/20 | 0.56 |
| ▸ | TNNI3K | Q59H18 | 5/20 | 0.55 |
| ▸ | BRAF | P15056 | 3/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1060507 | 0.83 | MKNK1 (0.72) | RAB9ASMN1; SMN2HTTHSD17B10TSHR | |
| SCHEMBL4917996 | 0.76 | SMN1; SMN2 (0.71) | RAB9ASMN1; SMN2HTTHSD17B10TSHR | |
| SCHEMBL4922640 | 0.76 | SMN1; SMN2 (1.00) | RAB9ASMN1; SMN2HTTHSD17B10TSHR | |
| SCHEMBL4913665 | 0.76 | SMN1; SMN2 (0.71) | RAB9ASMN1; SMN2HTTHSD17B10TSHR | |
| SCHEMBL4923320 | 0.76 | SMN1; SMN2 (0.71) | RAB9ASMN1; SMN2HTTHSD17B10TSHR | |
| SCHEMBL4921641 | 0.75 | MKNK1 (0.73) | RAB9ASMN1; SMN2HTTHSD17B10TSHR | |
| SCHEMBL4922517 | 0.75 | MKNK1 (1.00) | RAB9ASMN1; SMN2HTTHSD17B10TSHR | |
| SCHEMBL4926098 | 0.75 | MKNK1 (0.73) | RAB9ASMN1; SMN2HTTHSD17B10TSHR | |
| SCHEMBL4923804 | 0.75 | MKNK1 (0.73) | RAB9ASMN1; SMN2HTTHSD17B10TSHR | |
| SCHEMBL4921871 | 0.73 | SMN1; SMN2 (1.00) | RAB9ASMN1; SMN2HTTHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3104706-A1 | COMPOSITIONS AND METHODS USING THE SAME FOR TREATMENT OF NEURODEGENERATIVE AND MITOCHONDRIAL DISEASE | Mitokinin LLC (US) | 2016-12-21 | — | — | EP | disclosed |
| WO-2015123365-A1 | COMPOSITIONS AND METHODS USING THE SAME FOR TREATMENT OF NEURODEGENERATIVE AND MITOCHONDRIAL DISEASE | MITOKININ LLC (US) | 2015-08-20 | — | — | WO | disclosed |