Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.72 |
| ▸ | RAB9A | P51151 | 6/20 | 0.69 |
| ▸ | HTT | P42858 | 4/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | BRAF | P15056 | 3/20 | 0.69 |
| ▸ | TOP2A | P11388 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | GFER | P55789 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29501954 | 0.85 | LMNA (0.60) | MKNK1RAB9AHTTSMN1; SMN2MAPK1 | |
| SCHEMBL4923804 | 0.84 | MKNK1 (0.73) | MKNK1RAB9AHTTSMN1; SMN2MAPK1 | |
| SCHEMBL4921641 | 0.84 | MKNK1 (0.73) | MKNK1RAB9AHTTSMN1; SMN2MAPK1 | |
| SCHEMBL4926098 | 0.84 | MKNK1 (0.73) | MKNK1RAB9AHTTSMN1; SMN2MAPK1 | |
| SCHEMBL4922517 | 0.84 | MKNK1 (1.00) | MKNK1RAB9AHTTSMN1; SMN2MAPK1 | |
| SCHEMBL17009458 | 0.83 | RAB9A (0.61) | MKNK1RAB9AHTTSMN1; SMN2MAPK1 | |
| SCHEMBL4917996 | 0.82 | SMN1; SMN2 (0.71) | MKNK1RAB9AHTTSMN1; SMN2MAPK1 | |
| SCHEMBL4913665 | 0.82 | SMN1; SMN2 (0.71) | MKNK1RAB9AHTTSMN1; SMN2MAPK1 | |
| SCHEMBL4923320 | 0.82 | SMN1; SMN2 (0.71) | MKNK1RAB9AHTTSMN1; SMN2MAPK1 | |
| SCHEMBL4922640 | 0.82 | SMN1; SMN2 (1.00) | MKNK1RAB9AHTTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117597021-A | Method for high-volume production of polyphenols from red lettuce and use thereof | 新格诺康植物技术公司 | 2024-02-23 | — | — | CN | claimed |
| CN-116076620-A | Application of polyphenol lettuce in animal feed | 浙江迦美善植物科技有限公司 | 2023-05-09 | — | — | CN | claimed |
| CN-110882290-A | Application of extract of rhinacanthus nasutus callus, method for inducing and proliferating rhinacanthus nasutus callus and culture medium | 大江生医股份有限公司 | 2020-03-17 | — | — | CN | claimed |
| CN-109907317-A | For adjusting the dendrobium candidum extract and preparation method thereof of skin metabolism | 大江生医股份有限公司 | 2019-06-21 | — | — | CN | claimed |
| CN-104447746-A | Compound for activating AMPK and application thereof | HUAAN MEDICAL CO LTD | 2015-03-25 | — | — | CN | claimed |
| US-20140303112-A1 | Method for treating disease or condition susceptible to amelioration by AMPK activators and compounds of formula which are useful to activate AMP-activated protein kinase (AMPK) | ENERGENESIS BIOMEDICAL CO., LTD (TW) | 2014-10-09 | — | — | US | claimed |
| CN-102037157-B | Adhesion promotion of metal to laminate with a multi-functional compound | ENTHONE | 2014-05-28 | — | — | CN | claimed |
| EP-2173173-B1 | SUBSTITUTED 6-ANILINOPURINE DERIVATIVES AS INHIBITORS OF CYTOKININ OXIDASE/DEHYDROGENASE AND PREPARATIONS CONTAINING THESE DERIVATIVES | UNIV PALACKEHO (CZ) | 2013-07-24 | — | — | EP | claimed |
| EP-2546387-A1 | Adhesion promotion of metal to laminate with a multi-functional compound | Enthone, Inc. (US) | 2013-01-16 | — | — | EP | claimed |
| EP-2274460-B1 | ADHESION PROMOTION OF METAL TO LAMINATE WITH A MULTI-FUNCTIONAL COMPOUND | ENTHONE (US) | 2012-10-10 | — | — | EP | claimed |
| CN-102037157-A | Adhesion promotion of metal to laminate with a multi-functional compound | ENTHONE | 2011-04-27 | — | — | CN | claimed |
| EP-2274460-A1 | ADHESION PROMOTION OF METAL TO LAMINATE WITH A MULTI-FUNCTIONAL COMPOUND HAFTFORDERUNG VON METALL ZU LAMINATEN MIT EINER MULTIFUNKTIONELLEN | Enthone, Inc. (US) | 2011-01-19 | — | — | EP | claimed |
| US-20100190806-A1 | SUBSTITUTED 6-ANILINOPURINE DERIVATIVES AS INHIBITORS OF CYTOKININ OXIDASE/DEHYDROGENASE AND PREPARATIONS CONTAINING THESE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2010-07-29 | — | — | US | claimed |
| EP-2173173-A2 | SUBSTITUTED 6-ANILINOPURINE DERIVATIVES AS INHIBITORS OF CYTOKININ OXIDASE/DEHYDROGENASE AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita palackeho V Olomouci (CZ) | 2010-04-14 | — | — | EP | claimed |
| WO-2009117734-A1 | ADHESION PROMOTION OF METAL TO LAMINATE WITH A MULTI-FUNCTIONAL COMPOUND HAFTFORDERUNG VON METALL ZU LAMINATEN MIT EINER MULTIFUNKTIONELLEN | ENTHONE INC. (US) | 2009-09-24 | — | — | WO | claimed |
| WO-2009003428-A2 | SUBSTITUTED 6-ANILINOPURINE DERIVATIVES AS INHIBITORS OF CYTOKININ OXIDASE/DEHYDROGENASE AND PREPARATIONS CONTAINING THESE DERIVATIVES | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2009-01-08 | — | — | WO | claimed |
| US-20050043328-A1 | Heterocyclic compound based on n6-substituted adenine, methods, of their preparation, their use for preparation of drugs, cosmetic preparations and growth regulators, pharmaceutical preparations, cosmetic preparations and growth regulators containing these compounds | USTAV EPERIMENTALNI BOTANIKY AKADEMI VED CESKE REPUBILIKY (CZ) | 2005-02-24 | — | — | US | claimed |
| CN-1556808-A | Based on N6Heterocyclic compounds of substituted adenine, process for their preparation, their use for the preparation of medicaments, cosmetic preparations and growth regulators, pharmaceutical preparations, cosmetic preparations and growth regulators containing these compounds | �ݿ˹�����������ʵ��ֲ��ѧ�� | 2004-12-22 | — | — | CN | claimed |
| EP-1419157-A2 | HETEROCYCLIC COMPOUND BASED ON N sp 6 /sp −SUBSTITUTED ADENINE, METHODS OF THEIR PREPARATION, THEIR USE FOR PREPARATION OF DRUGS, COSMETIC PREPARATIONS AND GROWTH REGULATORS, PHARMACEUTICAL PREPARATIONS, COSMETIC PREPARATIONS AND GROWTH REGULATORS CONTAINING THESE | Ustav Experimentalni Botaniky Akademie ved Ceské Republiky (CZ) | 2004-05-19 | — | — | EP | claimed |
| WO-2003040144-A2 | HETEROCYCLIC COMPOUND BASED ON N6-SUBSTITUTED ADENINE, METHODS OF THEIR PREPARATION, THEIR USE FOR PREPARATION OF DRUGS, COSMETIC PREPARATIONS AND GROWTH REGULATORS, PHARMACEUTICAL PREPARATIONS, COSMETIC PREPARATIONS AND GROWTH REGULATORS CONTAINING THESE COMPOUNDS | USTAV EXPERIMENTALNI BOTANIKY AKADEMIE VED CESKE REPUBLIKY (CZ) | 2003-05-15 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140303112-A1 | Method for treating disease or condition susceptible to amelioration by AMPK activators and compounds of formula which are useful to activate AMP-activated protein kinase (AMPK) | PRKAG2, PRKAB2, PRKAG1 | MKNK1 233/4885RAB9A 2154/4885HTT 3291/4885 |
| US-20050043328-A1 | Heterocyclic compound based on n6-substituted adenine, methods, of their preparation, their use for preparation of drugs, cosmetic preparations and growth regulators, pharmaceutical preparations, cosmetic preparations and growth regulators containing these compounds | ATIC, UMPS, CCNB1 | MKNK1 1920/4885RAB9A 1756/4885HTT 1133/4885 |
| US-20100190806-A1 | SUBSTITUTED 6-ANILINOPURINE DERIVATIVES AS INHIBITORS OF CYTOKININ OXIDASE/DEHYDROGENASE AND PREPARATIONS CONTAINING THESE DERIVATIVES | DPYD, XDH, APRT | MKNK1 3750/4885RAB9A 3935/4885HTT 4615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.