Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1697302 | 0.96 | CNR2 (0.34) | CNR2 | |
| SCHEMBL24586822 | 0.74 | — | — | |
| SCHEMBL1701094 | 0.74 | — | — | |
| SCHEMBL14721836 | 0.72 | — | — | |
| SCHEMBL24587224 | 0.72 | — | — | |
| SCHEMBL14721148 | 0.71 | — | — | |
| SCHEMBL24587033 | 0.70 | — | — | |
| (-)-Camphene SCHEMBL8819262 | 0.68 | CNR2 (0.42) | CNR2 | |
| (-)-Camphene SCHEMBL6552600 | 0.68 | CNR2 (0.42) | CNR2 | |
| (-)-Camphene SCHEMBL6675451 | 0.68 | CNR2 (0.42) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10716770-B2 | Nicotinic receptor non-competitive antagonists | CATALYST BIOSCIENCES, INC. (US) | 2020-07-21 | — | — | US | disclosed |
| US-20190254991-A1 | Nicotinic Receptor Non-Competitive Antagonists | CATALYST BIOSCIENCES INC (US) | 2019-08-22 | — | — | US | disclosed |
| US-10258582-B2 | Nicotinic receptor non-competitive antagonists | CATALYST BIOSCIENCES, INC. (US) | 2019-04-16 | — | — | US | disclosed |
| US-20180271806-A1 | NICOTINIC RECEPTOR NON-COMPETITIVE ANTAGONISTS | CATALYST BIOSCIENCES, INC. | 2018-09-27 | — | — | US | disclosed |
| US-20170071878-A1 | NICOTINIC RECEPTOR NON-COMPETITIVE ANTAGONISTS | CATALYST BIOSCIENCES INC (US) | 2017-03-16 | — | — | US | disclosed |
| EP-2576496-B1 | NICOTINIC RECEPTOR NON-COMPETITIVE ANTAGONISTS | CATALYST BIOSCIENCES INC (US) | 2017-03-08 | — | — | EP | disclosed |
| US-20140315877-A1 | NICOTINIC RECEPTOR NON-COMPETITIVE ANTAGONISTS | TARGACEPT INC (US) | 2014-10-23 | — | — | US | disclosed |
| US-8809397-B2 | Nicotinic receptor non-competitive antagonists | TARGACEPT, INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-20130203860-A1 | NICOTINIC RECEPTOR NON-COMPETITIVE ANTAGONISTS | TARGACEPT, INC. | 2013-08-08 | — | — | US | disclosed |
| EP-2576496-A1 | NICOTINIC RECEPTOR NON-COMPETITIVE ANTAGONISTS | Targacept, Inc. (US) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011149859-A1 | NICOTINIC RECEPTOR NON-COMPETITIVE ANTAGONISTS | TARGACEPT, INC. (US) | 2011-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10258582-B2 | Nicotinic receptor non-competitive antagonists | CHRNA5, CHRNA2, CHRNG | CNR2 39/4885 |
| US-20180271806-A1 | NICOTINIC RECEPTOR NON-COMPETITIVE ANTAGONISTS | CHRNA5, CHRNA2, CHRNG | CNR2 39/4885 |
| US-20130203860-A1 | NICOTINIC RECEPTOR NON-COMPETITIVE ANTAGONISTS | CHRNA5, CHRNA2, CHRNG | CNR2 39/4885 |
| US-20170071878-A1 | NICOTINIC RECEPTOR NON-COMPETITIVE ANTAGONISTS | CHRNA5, CHRNA2, CHRNG | CNR2 39/4885 |
| US-10716770-B2 | Nicotinic receptor non-competitive antagonists | CHRNA5, CHRNA2, CHRNG | CNR2 38/4885 |
| US-20190254991-A1 | Nicotinic Receptor Non-Competitive Antagonists | CHRNA5, CHRNA2, CHRNG | CNR2 38/4885 |
| US-20140315877-A1 | NICOTINIC RECEPTOR NON-COMPETITIVE ANTAGONISTS | CHRNA5, CHRNA2, CHRNG | CNR2 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.