Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.57 |
| ▸ | SCN1A | P35498 | 2/20 | 0.57 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.57 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | HRH2 | P25021 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.57 |
| ▸ | HRH1 | P35367 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963488 | 0.91 | PHLPP2 (0.83) | PHLPP2ALDH1A1MAPTGAALMNA | |
| SCHEMBL8487897 | 0.86 | PHLPP2 (0.71) | PHLPP2ALDH1A1MAPTGAALMNA | |
| SCHEMBL1107147 | 0.84 | PHLPP2 (0.73) | PHLPP2ALDH1A1MAPTGAALMNA | |
| SCHEMBL8963375 | 0.84 | PHLPP2 (0.73) | PHLPP2ALDH1A1MAPTGAALMNA | |
| SCHEMBL8639938 | 0.84 | PHLPP2 (0.73) | PHLPP2ALDH1A1MAPTGAALMNA | |
| SCHEMBL10777193 | 0.83 | PHLPP2 (0.71) | PHLPP2ALDH1A1MAPTGAALMNA | |
| SCHEMBL34468111 | 0.83 | PHLPP2 (0.71) | PHLPP2ALDH1A1MAPTGAALMNA | |
| SCHEMBL4835480 | 0.83 | PHLPP2 (1.00) | PHLPP2ALDH1A1MAPTGAALMNA | |
| SCHEMBL9481715 | 0.83 | GAA (0.82) | PHLPP2ALDH1A1MAPTGAALMNA | |
| SCHEMBL65544 | 0.82 | PHLPP2 (0.70) | PHLPP2ALDH1A1MAPTGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161018-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2011-12-29 | — | — | WO | disclosed |