Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289780 | 0.82 | AKR1B1 (0.50) | AKR1B1CYP1A2TDP1DUSP3PTPN5 | |
| Acetic Acid SCHEMBL5540371 | 0.77 | AKR1B1 (0.46) | AKR1B1CYP1A2TDP1DUSP3PTPN5 | |
| SCHEMBL28991119 | 0.77 | AKR1B1 (0.43) | AKR1B1CYP1A2TDP1DUSP3PTPN5 | |
| SCHEMBL28900013 | 0.73 | MAPT (0.41) | CYP1A2SRCKDM4EMAPTPTGS2 | |
| SCHEMBL1873283 | 0.73 | AKR1B1 (0.60) | AKR1B1CYP1A2TDP1DUSP3PTPN5 | |
| Benzene SCHEMBL1146112 | 0.73 | AKR1B1 (0.60) | AKR1B1CYP1A2TDP1DUSP3PTPN5 | |
| Iodobenzene SCHEMBL31189210 | 0.72 | AKR1B1 (0.44) | AKR1B1CYP1A2TDP1DUSP3PTPN5 | |
| SCHEMBL5543109 | 0.72 | AKR1B1 (0.41) | AKR1B1CYP1A2TDP1DUSP3PTPN5 | |
| SCHEMBL31042841 | 0.71 | HSD17B10 (0.53) | TDP1KDM4EMAPTCAMK2ACA2 | |
| SCHEMBL29101379 | 0.71 | AKR1B1 (0.46) | AKR1B1CYP1A2TDP1DUSP3PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2515837-B1 | COMPOSITION FOR DYEING KERATIN FIBERS, INCLUDING AT LEAST ONE ORTHO-DIPHENOL DERIVATIVE, ONE PARTICULAR METAL DERIVATIVE, AND ONE ALKALINIZING AGENT | OREAL (FR) | 2018-11-07 | — | — | EP | claimed |
| WO-2012084473-A1 | PROCESS FOR DYEING KERATIN FIBRES USING RESORCINOL DERIVATIVES, SULFATE SALTS, AN OXIDIZING AGENT AND A BASIFYING AGENT | L'OREAL (FR) | 2012-06-28 | — | — | WO | claimed |
| WO-2011157666-A1 | COSMETIC USE OF A NATURAL EXTRACT DERIVED FROM BEETROOT PEEL FOR DYEING HAIR COMPOSITION COMPRISING THE EXTRACT, AN OXIDIZING AGENT, A BASIFYING AGENT AN OPTIONAL METALLIC DERIVATIVE | L'OREAL (FR) | 2011-12-22 | — | — | WO | claimed |
| WO-2017134132-A1 | USE OF POLYAMINE COMPOUNDS WITH AN ALIPHATIC LINKER IN THE PRESENCE OF OXIDIZING AGENTS FOR TREATING KERATIN FIBRES | L'OREAL (FR) | 2017-08-10 | — | — | WO | disclosed |
| WO-2017108551-A1 | HAIR DYEING PROCESS USING NATURAL DYE, OXIDIZING AGENT, FATTY SUBSTANCES AND SURFACTANTS, COMPOSITION AND KIT COMPRISING THE INGREDIENTS | L'OREAL (FR) | 2017-06-29 | — | — | WO | disclosed |
| WO-2017108696-A1 | USE OF PARTICULAR POLYAMINE COMPOUNDS IN THE PRESENCE OF OXIDIZING AGENTS FOR TREATING KERATIN FIBRES | L'OREAL (FR) | 2017-06-29 | — | — | WO | disclosed |
| US-8608808-B2 | Composition for dyeing keratin fibers, including at least one ortho-diphenol derivative, one particular metal derivative, and one alkalinizing agent | L'OREAL (FR) | 2013-12-17 | — | — | US | disclosed |
| US-20130139846-A1 | COMPOSITION FOR DYEING KERATIN FIBERS, INCLUDING AT LEAST ONE ORTHO-DIPHENOL DERIVATIVE, ONE PARTICULAR METAL DERIVATIVE, AND ONE ALKALINIZING AGENT | L'OREAL (FR) | 2013-06-06 | — | — | US | disclosed |
| WO-2012084473-A1 | PROCESS FOR DYEING KERATIN FIBRES USING RESORCINOL DERIVATIVES, SULFATE SALTS, AN OXIDIZING AGENT AND A BASIFYING AGENT | L'OREAL (FR) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012084472-A1 | PROCESS FOR DYEING KERATIN FIBRES USING HYDROXYBENZALDEHYDE DERIVATIVES, OXIDIZING AGENTS AND ALKALINIZING AGENTS IN THE PRESENCE OF HEAT | L'OREAL (FR) | 2012-06-28 | — | — | WO | disclosed |
| WO-2011157666-A1 | COSMETIC USE OF A NATURAL EXTRACT DERIVED FROM BEETROOT PEEL FOR DYEING HAIR COMPOSITION COMPRISING THE EXTRACT, AN OXIDIZING AGENT, A BASIFYING AGENT AN OPTIONAL METALLIC DERIVATIVE | L'OREAL (FR) | 2011-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130139846-A1 | COMPOSITION FOR DYEING KERATIN FIBERS, INCLUDING AT LEAST ONE ORTHO-DIPHENOL DERIVATIVE, ONE PARTICULAR METAL DERIVATIVE, AND ONE ALKALINIZING AGENT | KRT18, DSG1, DSC1 | AKR1B1 315/4885CYP1A2 328/4885TDP1 3513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.