Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.51 |
| ▸ | GGT1 | P19440 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9126196 | 0.84 | KMT2A (0.55) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL17673999 | 0.82 | KMT2A (0.71) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL31588107 | 0.82 | KMT2A (0.71) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL30727560 | 0.81 | TSHR (0.67) | KDM4EALDH1A1CYP1A2CYP2C9KMT2A | |
| SCHEMBL29696138 | 0.81 | TSHR (0.67) | KDM4EALDH1A1CYP1A2CYP2C9KMT2A | |
| SCHEMBL11208120 | 0.81 | KDM4E (0.79) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL78205 | 0.81 | TSHR (0.67) | KDM4EALDH1A1CYP1A2CYP2C9KMT2A | |
| SCHEMBL9263396 | 0.81 | ESR2 (0.62) | KDM4EALDH1A1HSD17B10HPGDKMT2A | |
| SCHEMBL827585 | 0.80 | ALDH1A1 (0.59) | KDM4EALDH1A1CYP1A2CYP2C9KMT2A | |
| SCHEMBL11779675 | 0.80 | KMT2A (0.56) | KDM4EALDH1A1LMNAKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3104835-A1 | PULVURENT EFFERVESCENT TOPICAL TREATMENT COMPOSITION | Reckitt Benckiser LLC (US) | 2016-12-21 | — | — | EP | disclosed |
| WO-2015121659-A1 | PULVURENT EFFERVESCENT TOPICAL TREATMENT COMPOSITION | RECKITT BENCKISER LLC (US) | 2015-08-20 | — | — | WO | disclosed |