Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4201843 | 0.81 | KCNH2 (0.48) | GAAHTR2AMCHR1KCNH2SIGMAR1 | |
| SCHEMBL2847275 | 0.74 | GAA (0.60) | GAACYP2D6MCHR1PRKAA2KCNH2 | |
| SCHEMBL4526865 | 0.73 | KCNH2 (0.48) | HTR2AMCHR1MAOBKCNH2SIGMAR1 | |
| SCHEMBL4267387 | 0.70 | GAA (0.64) | GAAMAOBKCNH2ACHEKDM4E | |
| SCHEMBL4209657 | 0.69 | KCNH2 (0.53) | HTR2AKCNH2SIGMAR1ACHEOPRM1 | |
| SCHEMBL4261542 | 0.69 | GAA (0.66) | GAAHTR2AMAOBPRKAA2KCNH2 | |
| SCHEMBL4259748 | 0.69 | GAA (0.66) | GAACYP2D6MAOBKCNH2KDM4E | |
| SCHEMBL4267783 | 0.69 | GAA (0.66) | GAAHTR2AMAOBPRKAA2KCNH2 | |
| SCHEMBL4207304 | 0.68 | KCNH2 (0.45) | HTR2AKCNH2SIGMAR1ACHEKDM4E | |
| SCHEMBL20527292 | 0.68 | GAA (0.64) | GAAHTR2AMAOBPRKAA2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250154467-A1 | CREATION OF VASCULARIZED BIOLOGICAL STRUCTURES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2025-05-15 | — | — | US | disclosed |
| US-20250092358-A1 | In Vitro Breeding Systems and Methods in Livestock | ABS GLOBAL, INC. (US) | 2025-03-20 | — | — | US | disclosed |
| CN-117412668-A | Livestock in vitro breeding system and method | ABS全球公司 | 2024-01-16 | — | — | CN | disclosed |
| WO-2023164242-A1 | CREATION OF VASCULARIZED BIOLOGICAL STRUCTURES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-08-31 | — | — | WO | disclosed |
| US-20230159894-A1 | GENERATING POPULATIONS OF HUMAN BLOOD AND BLOOD VESSEL PROGENITORS FROM PLURIPOTENT STEM CELLS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2023-05-25 | — | — | US | disclosed |
| US-20220348877-A1 | GENERATION OF QUIESCENT CARDIAC FIBROBLASTS FROM HUMAN INDUCED PLURIPOTENT STEM CELLS FOR IN VITRO MODELING OF CARDIAC FIBROSIS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2022-11-03 | — | — | US | disclosed |
| EP-3104873-B1 | FGF-8 FOR USE IN TREATING DISEASES OR DISORDERS OF ENERGY HOMEOSTASIS | UNIV MUENCHEN TECH (DE) | 2019-09-04 | — | — | EP | disclosed |
| US-20170258874-A1 | FGF-8 FOR USE IN TREATING DISEASES OR DISORDERS OF ENERGY HOMEOSTASIS | Technische Universität München (DE) | 2017-09-14 | — | — | US | disclosed |
| EP-3104873-A1 | FGF-8 FOR USE IN TREATING DISEASES OR DISORDERS OF ENERGY HOMEOSTASIS | Technische Universität München (DE) | 2016-12-21 | — | — | EP | disclosed |
| WO-2015121457-A1 | FGF-8 FOR USE IN TREATING DISEASES OR DISORDERS OF ENERGY HOMEOSTASIS | WESTPHAL SÖREN (DE) | 2015-08-20 | — | — | WO | disclosed |