Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4526865 | 0.92 | KCNH2 (0.48) | KCNH2GPR119OPRM1KDM4EMCHR1 | |
| SCHEMBL4209657 | 0.89 | KCNH2 (0.53) | KCNH2GPR119OPRM1DRD2HTR2A | |
| SCHEMBL4207304 | 0.87 | KCNH2 (0.45) | KCNH2GPR119KDM4EDRD2HTR2A | |
| SCHEMBL5252348 | 0.82 | KCNH2 (0.46) | KCNH2GPR119GAAOPRM1OPRD1 | |
| SCHEMBL17010771 | 0.81 | GAA (0.45) | KCNH2GAAOPRM1OPRD1OPRK1 | |
| SCHEMBL13478931 | 0.80 | KCNH2 (0.54) | KCNH2GPR119GAAOPRM1OPRD1 | |
| SCHEMBL13928769 | 0.79 | CCR5 (0.41) | KCNH2HTR2AHTR2CALDH1A1CCR5 | |
| SCHEMBL4207407 | 0.79 | OPRM1 (0.50) | KCNH2OPRM1OPRD1OPRK1DRD2 | |
| SCHEMBL4202240 | 0.79 | CCR5 (0.37) | CCR5 | |
| SCHEMBL5882245 | 0.79 | CCR5 (0.33) | KCNH2GPR119OPRD1OPRK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125650-A1 | METHODS AND COMPOSITIONS FOR GENERATING HEPATOCYTES | TRAILHEAD BIOSYSTEMS INC (US) | 2026-05-07 | — | — | US | claimed |
| US-20260092257-A1 | METHODS AND COMPOSITIONS FOR GENERATING HEMATOPOIETIC PROGENITOR CELLS | TRAILHEAD BIOSYSTEMS INC. | 2026-04-02 | — | — | US | claimed |
| US-20250304916-A1 | METHODS AND COMPOSITIONS FOR GENERATING VASCULAR LEPTOMENINGEAL CELLS | TRAILHEAD BIOSYSTEMS INC (US) | 2025-10-02 | — | — | US | claimed |
| EP-4599048-A1 | COMPOSITIONS AND METHODS FOR SMALL MOLECULE BASED EXPANSION OF PLURIPOTENT STEM CELLS | Trailhead Biosystems Inc. (US) | 2025-08-13 | — | — | EP | claimed |
| EP-4577641-A1 | METHODS AND COMPOSITIONS FOR GENERATING HEMOGENIC ENDOTHELIAL CELLS FROM PLURIPOTENT STEM CELLS | Trailhead Biosystems Inc. (US) | 2025-07-02 | — | — | EP | claimed |
| EP-4577639-A1 | METHODS AND COMPOSITIONS FOR SMALL MOLECULE BASED PANCREATIC BETA CELL INDUCTION | Trailhead Biosystems Inc. (US) | 2025-07-02 | — | — | EP | claimed |
| EP-4569090-A2 | METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS | Trailhead Biosystems Inc. (US) | 2025-06-18 | — | — | EP | claimed |
| EP-4558612-A1 | METHODS AND COMPOSITIONS FOR GENERATING ENDOTHELIAL CELLS FROM PLURIPOTENT STEM CELLS | Trailhead Biosystems Inc. (US) | 2025-05-28 | — | — | EP | claimed |
| CN-119768510-A | Methods and compositions for producing hematopoietic endothelial cells from pluripotent stem cells | 特雷尔赫德生物系统股份有限公司 | 2025-04-04 | — | — | CN | claimed |
| US-20250092358-A1 | In Vitro Breeding Systems and Methods in Livestock | ABS GLOBAL, INC. (US) | 2025-03-20 | — | — | US | claimed |
| US-20240009248-A1 | METHODS FOR GENERATING NEURAL PROGENITOR CELLS WITH A SPINAL CORD IDENTITY | UNIVERSITY HEALTH NETWORK (CA) | 2024-01-11 | — | — | US | claimed |
| EP-4211229-A1 | METHODS FOR GENERATING NEURAL PROGENITOR CELLS WITH A SPINAL CORD IDENTITY | University Health Network (CA) | 2023-07-19 | — | — | EP | claimed |
| CN-116194127-A | Methods of generating neural progenitor cells with spinal cord properties | 大学健康网络 | 2023-05-30 | — | — | CN | claimed |
| CN-109517783-B | Full-small-molecule culture medium for liver organoid culture and application thereof | 复旦大学 | 2022-12-16 | — | — | CN | claimed |
| WO-2022251549-A1 | IN VITRO BREEDING SYSTEMS AND METHODS IN LIVESTOCK | ABS GLOBAL, INC. (US) | 2022-12-01 | — | — | WO | claimed |
| WO-2022051847-A9 | METHODS FOR GENERATING NEURAL PROGENITOR CELLS WITH A SPINAL CORD IDENTITY | UNIVERSITY HEALTH NETWORK (CA) | 2022-04-21 | — | — | WO | claimed |
| WO-2022051847-A1 | METHODS FOR GENERATING NEURAL PROGENITOR CELLS WITH A SPINAL CORD IDENTITY | UNIVERSITY HEALTH NETWORK (CA) | 2022-03-17 | — | — | WO | claimed |
| US-7488738-B2 | Aminophenoxyacetic acid derivatives and pharmaceutical composition containing thereof | ASUBIO PHARMA CO., LTD. (JP) | 2009-02-10 | — | — | US | claimed |
| US-6998401-B2 | Aminophenoxyacetic acid derivatives and pharmaceutical composition containing thereof | SUNTORY LIMITED (JP) | 2006-02-14 | — | — | US | claimed |
| US-20050245574-A1 | Aminophenoxyacetic acid derivatives and pharmaceutical composition containing thereof | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2005-11-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260092257-A1 | METHODS AND COMPOSITIONS FOR GENERATING HEMATOPOIETIC PROGENITOR CELLS | FLT4, CSF3R, FGFR3 | KCNH2 4505/4885GPR119 409/4885GAA 593/4885 |
| US-20050245574-A1 | Aminophenoxyacetic acid derivatives and pharmaceutical composition containing thereof | CAMK2A, CAMK2B, SLC1A2 | KCNH2 554/4885GPR119 632/4885GAA 2706/4885 |
| US-20260125650-A1 | METHODS AND COMPOSITIONS FOR GENERATING HEPATOCYTES | WNT3A, GSK3B, GSK3A | KCNH2 4679/4885GPR119 286/4885GAA 2709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.