Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PAM | P19021 | 2/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26153348 | 0.79 | LMNA (0.47) | LMNAMAPTCES1CES2DGKA | |
| SCHEMBL16021725 | 0.79 | EGLN1 (0.42) | LMNAALDH1A1TSHRTDP1MEN1 | |
| SCHEMBL11285973 | 0.78 | CES1 (0.48) | LMNAMAPTCES1CES2DGKA | |
| SCHEMBL11509336 | 0.77 | CES1 (0.42) | LMNAMAPTCES1CES2DGKA | |
| SCHEMBL1003368 | 0.76 | CES1 (0.46) | LMNAMAPTCES1CES2DGKA | |
| SCHEMBL11564625 | 0.76 | CA1 (0.46) | LMNAMAPTCES1CES2DGKA | |
| SCHEMBL11565466 | 0.76 | CES1 (0.46) | LMNAMAPTCES1CES2DGKA | |
| SCHEMBL28597213 | 0.75 | TSHR (0.39) | LMNAMAPTDGKAMAPK1ALDH1A1 | |
| SCHEMBL8157293 | 0.75 | LMNA (0.52) | LMNAMAPTCES1CES2DGKA | |
| SCHEMBL28611018 | 0.75 | TSHR (0.35) | LMNAMAPTMAPK1TSHRPAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9110369-B2 | Photoacid generator, photoresist, coated substrate, and method of forming an electronic device | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2015-08-18 | — | — | US | disclosed |