Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | KDR | P35968 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14524469 | 1.00 | GAA (0.64) | GAAALDH1A1CYP3A4SMN1; SMN2TDP1 | |
| SCHEMBL13060910 | 0.86 | GAA (0.61) | GAAALDH1A1CYP3A4SMN1; SMN2TDP1 | |
| SCHEMBL13006831 | 0.85 | GAA (0.59) | GAAALDH1A1CYP3A4SMN1; SMN2TDP1 | |
| SCHEMBL12903624 | 0.81 | GAA (0.62) | GAAALDH1A1CYP3A4SMN1; SMN2TDP1 | |
| SCHEMBL12903578 | 0.81 | SMN1; SMN2 (0.76) | GAAALDH1A1CYP3A4SMN1; SMN2TDP1 | |
| Sulfamethazine SCHEMBL151305 | 0.78 | ALDH1A1 (1.00) | GAAALDH1A1CYP3A4SMN1; SMN2TDP1 | |
| Sulfamethazine SCHEMBL17256221 | 0.78 | ALDH1A1 (1.00) | GAAALDH1A1CYP3A4SMN1; SMN2TDP1 | |
| SCHEMBL9201996 | 0.78 | GAA (0.71) | GAAALDH1A1CYP3A4SMN1; SMN2TDP1 | |
| Sulfamethazine SCHEMBL29918086 | 0.78 | ALDH1A1 (1.00) | GAAALDH1A1CYP3A4SMN1; SMN2TDP1 | |
| SCHEMBL18292531 | 0.78 | GAA (0.71) | GAAALDH1A1CYP3A4SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160058776-A1 | ACTIVE AGENTS AND THEIR OLIGOMERS AND POLYMERS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2016-03-03 | — | — | US | disclosed |
| US-9108070-B2 | Active agents and their oligomers and polymers | POLYMERIX CORPORATION (US) | 2015-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160058776-A1 | ACTIVE AGENTS AND THEIR OLIGOMERS AND POLYMERS | ALG1, DDOST, IDUA | GAA 12/4885ALDH1A1 2906/4885CYP3A4 4554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.