SCHEMBL17012320

SCHEMBL17012320

c1ccc(N(c2ccc(-c3cccnc3)nc2)c2cccc(-c3ccc4c5c(cccc35)-c3ccccc3-4)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ PIM1 P11309 8/20 0.40
▸ PIM2 Q9P1W9 4/20 0.40
▸ PIM3 Q86V86 3/20 0.40
▸ CYP11B1 P15538 5/20 0.40
▸ CYP11B2 P19099 3/20 0.40
▸ CYP2A6 P11509 2/20 0.39
▸ CYP3A4 P08684 1/20 0.39
▸ FYN P06241 1/20 0.38
▸ CYP19A1 P11511 1/20 0.36
▸ DHPS P49366 1/20 0.36
▸ WNT1 P04628 2/20 0.35
▸ TGFBR1 P36897 1/20 0.35
▸ CLK2 P49760 1/20 0.35
▸ CLK3 P49761 1/20 0.35
▸ DYRK1A Q13627 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16485342 0.93 CYP11B1 (0.41) PIM1PIM2PIM3CYP11B1CYP11B2
SCHEMBL16485077 0.92 PIM1 (0.38) PIM1PIM2PIM3CYP11B1CYP11B2
SCHEMBL20016808 0.92 PIK3CA (0.37) PIM1PIM2PIM3CYP11B1CYP11B2
SCHEMBL17012323 0.91 CYP11B1 (0.37) CYP11B1CYP11B2DYRK1A
SCHEMBL17132510 0.90 CYP11B1 (0.39) CYP11B1CYP11B2FYNWNT1TGFBR1
SCHEMBL16483925 0.90 CYP11B1 (0.43) PIM1PIM2PIM3CYP11B1CYP11B2
SCHEMBL20016827 0.89 FYN (0.35) PIM1PIM2PIM3CYP11B1CYP11B2
SCHEMBL16484087 0.89 CYP11B1 (0.40) CYP11B1CYP11B2FYNCYP19A1DHPS
SCHEMBL16485331 0.89 CYP11B1 (0.43) CYP11B1CYP11B2CYP2A6CYP3A4FYN
SCHEMBL16485363 0.89 CYP11B1 (0.45) CYP11B1CYP11B2CYP2A6CYP3A4FYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2907803-B1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT TORAY INDUSTRIES (JP) 2021-08-18 — — EP disclosed
US-9935273-B2 Fluoranthene derivative, light-emitting device material containing same, and light-emitting device TORAY INDUSTRIES, INC. (JP) 2018-04-03 — — US disclosed
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2015-10-01 — — US disclosed
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2015-10-01 — — US disclosed
EP-2907803-A1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT Toray Industries, Inc. (JP) 2015-08-19 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE FMNL1, AFF2, LEF1 PIM1 3467/4885PIM2 2504/4885PIM3 3723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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