Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexadecane SCHEMBL2039121 | 1.00 | TSHR (1.00) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Undecane SCHEMBL20767628 | 1.00 | TSHR (1.00) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Octane SCHEMBL1585515 | 1.00 | TSHR (1.00) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Dodecane SCHEMBL4052434 | 1.00 | TSHR (1.00) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Tetradecane SCHEMBL25387874 | 1.00 | TSHR (1.00) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Hexadecane SCHEMBL23499901 | 1.00 | TSHR (1.00) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Decane SCHEMBL23499900 | 1.00 | TSHR (1.00) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Tetradecane SCHEMBL23924271 | 1.00 | TSHR (1.00) | TSHRTHRBLMNADNM1ALDH1A1 | |
| SCHEMBL23854647 | 1.00 | TSHR (1.00) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Decane SCHEMBL2999362 | 1.00 | TSHR (1.00) | TSHRTHRBLMNADNM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058514-A1 | COLD ACTIVE ENZYME AND METHOD THEREOF | UNIVERSITY PUTRA MALAYSIA (MY) | 2012-03-08 | — | — | US | claimed |
| CN-116715672-A | Trifluoromethyl modified macrocyclic supermolecule main body molecular cup and metal molecular cup, and preparation methods and applications thereof | 上海大学 | 2023-09-08 | — | — | CN | disclosed |
| US-20210013491-A1 | NANOSILICON MATERIAL PREPARATION FOR FUNCTIONALIZED GROUP IVA PARTICLE FRAMEWORKS | PARACLETE ENERGY, INC. | 2021-01-14 | — | — | US | disclosed |
| US-20170338476-A1 | NANOSILICON MATERIAL PREPARATION FOR FUNCTIONALIZED GROUP IVA PARTICLE FRAMEWORKS | PARACLETE ENERGY, INC. | 2017-11-23 | — | — | US | disclosed |
| EP-3108525-A1 | NANOSILICON MATERIAL PREPARATION FOR FUNCTIONALIZED GROUP IVA PARTICLE FRAMEWORKS | Kratos LLC (US) | 2016-12-28 | — | — | EP | disclosed |
| US-20150263342-A1 | NANOSILICON MATERIAL PREPARATION FOR FUNCTIONALIZED GROUP IVA PARTICLE FRAMEWORKS | PARACLETE ENERGY, INC. | 2015-09-17 | — | — | US | disclosed |
| US-20150243973-A1 | NANOSILICON MATERIAL PREPARATION FOR FUNCTIONALIZED GROUP IVA PARTICLE FRAMEWORKS | PARACLETE ENERGY, INC. | 2015-08-27 | — | — | US | disclosed |
| US-8623996-B2 | Cold active enzyme and method thereof | UNIVERSITY PUTRA MALAYSIA (MY) | 2014-01-07 | — | — | US | disclosed |
| CN-101970541-B | Copolymer comprising non-charged hydrophilic block and cationic polyamino acid block having hydrophobic group introduced into part of side chain, and use thereof | UNIV TOKYO | 2013-12-04 | — | — | CN | disclosed |
| US-20120058514-A1 | COLD ACTIVE ENZYME AND METHOD THEREOF | UNIVERSITY PUTRA MALAYSIA (MY) | 2012-03-08 | — | — | US | disclosed |
| CN-101970541-A | Copolymer comprising non-charged hydrophilic block and cationic polyamino acid block having hydrophobic group introduced into part of side chain, and use thereof | UNIV TOKYO | 2011-02-09 | — | — | CN | disclosed |
| CN-1411902-A | Diamond water turbid liquid with good dispersion stabilizing property, metal film containing diamond and its products | FUJIMURA TADAMASA (JP) | 2003-04-23 | — | — | CN | disclosed |
| US-6271165-B1 | SOLID COORDINATION CATALYST | THE DOW CHEMICAL COMPANY | 2001-08-07 | — | — | US | disclosed |
| US-4617057-A | AMINOORGANOSILANE, PERFLUORINATED ORGANIC COMPOUND AND RESIN | DOW CORNING CORPORATION (US) | 1986-10-14 | — | — | US | disclosed |
| US-4468479-A | FLAME RETARDANT, POLYURETHANES, POLYESTERS, FOAMS | ETHYL CORPORATION (US) | 1984-08-28 | — | — | US | disclosed |
| US-4285851-A | DISSOLVING AN IONOMER COPOLYMER BASED ON AN AMINE-TERMINATED POLYOXYALKYLENE GLYCOL AND SULFONATED ADDITION POLYMER IN A WATER-IMMISCIBLE SOLVENT; ADDING WATER; HIGH SPEED; OIL WELLS | EXXON RESEARCH & ENGINEERING CO. (US) | 1981-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170338476-A1 | NANOSILICON MATERIAL PREPARATION FOR FUNCTIONALIZED GROUP IVA PARTICLE FRAMEWORKS | VCL, ANXA6, ITGA6 | TSHR 3010/4885THRB 4350/4885LMNA 71/4885 |
| US-20150263342-A1 | NANOSILICON MATERIAL PREPARATION FOR FUNCTIONALIZED GROUP IVA PARTICLE FRAMEWORKS | VCL, ANXA6, ITGA6 | TSHR 3010/4885THRB 4350/4885LMNA 71/4885 |
| US-20210013491-A1 | NANOSILICON MATERIAL PREPARATION FOR FUNCTIONALIZED GROUP IVA PARTICLE FRAMEWORKS | VCL, ANXA6, ITGA6 | TSHR 3010/4885THRB 4350/4885LMNA 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.