ITGA6

Integrin alpha-6 · P23229 · ITGA6 on Sugi Atlas →

0 patent compounds predicted against ITGA6, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to ITGA6 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Monoclonal Antibody Therapy in Treating Patients With Advanced Colorectal Cancer PHASE1/PHASE2COMPLETED
68 Ga-NODAGA-E[c(RGDγK)]2: Positron Emission Tomography Tracer for Imaging of Myocardial Angiogenesis PHASE2COMPLETED
68 Ga-NODAGA-E[c(RGDγK)]2: Positron Emission Tomography Tracer for Imaging of Angiogenesis in Ischemic Heart Disease PHASE2UNKNOWN
Leniolisib for Immune Dysregulation in CVID PHASE2ACTIVE_NOT_RECRUITING
A Gene Therapy Trial to Evaluate the Safety and Efficacy of RP-L201 in Subjects With Leukocyte Adhesion Deficiency-I PHASE1WITHDRAWN
Molecularly Targeted Radionuclide Therapy Via the Integrin Alphavbeta6 PHASE1RECRUITING
Safety/Biomarker Study of CNTO 95 and Avastin in Solid Tumors PHASE1COMPLETED
An Open-label, Single-arm, Single-center Study to Evaluate the Diagnostic Efficacy of a Novel PET Probe, 68Ga-SFB6-ZN01, in Patients With Malignant Tumors EARLY_PHASE1NOT_YET_RECRUITING
68Ga-NOTA-PRGD2 PET/CT in Patients With Lung Injury and Pulmonary Fibrosis EARLY_PHASE1UNKNOWN
Integrin α6-targeted SPECT Imaging of Breast Cancer EARLY_PHASE1COMPLETED
68Ga-BNOTA-PRGD2 PET/CT in Patients With Rheumatoid Arthritis EARLY_PHASE1UNKNOWN
68Ga-BNOTA-PRGD2 PET/CT in Evaluation of Stroke EARLY_PHASE1UNKNOWN
68Ga-BNOTA-PRGD2 PET/CT in Diagnosis and Evaluation of Glioma EARLY_PHASE1UNKNOWN
99mTc-3PRGD2 SPECT/CT in Rheumatoid Arthritis Patients EARLY_PHASE1COMPLETED
68Ga-BNOTA-PRGD2 PET/CT in Healthy Volunteers and Lung Cancer Patients EARLY_PHASE1UNKNOWN
68Ga-BNOTA-PRGD2 PET/CT in Evaluation of Myocardial Infarction EARLY_PHASE1UNKNOWN
Potential Role of microRNA 410 and BIRC7 Pathways in Recurrent Spontaneous Miscarriage nanCOMPLETED
Anti-αIIbβ3 Immunization in Glanzmann Thrombasthenia: Prevalence and Associated Risk Factors: Thrombasthenia Anti-αIIbβ3 Antibodies Study (TAAS) nanCOMPLETED
Angiogenesis and Fibrosis in Aortic Stenosis nanCOMPLETED
Integrin αvβ6-targeted PET in Malignant Tumors nanRECRUITING
Angiogenesis and Fibrosis in Myocardial Infarction nanCOMPLETED
IMaging Pilot Study of the αvβ6 Integrin Radiotracer [18F]-A20FMDV2 in PAtients With Solid Cancer Types nanCOMPLETED
T Lymphocyte Subsets in Ulcerative Colitis nanNOT_YET_RECRUITING
The Role of Platelet Surface α2β1 Integrin Expression as a Risk Factor in Thrombotic and/or Bleeding Complications nanCOMPLETED
An Imaging Study in ER Negative Breast Cancer by Targeting αvβ6 nanWITHDRAWN
Short-Term Application of Tocilizumab Following Myocardial Infarction nanCOMPLETED
In-vivo Thrombus Imaging With 18F-GP1, a Novel Platelet PET Radiotracer nanCOMPLETED
Integrins and Protocadherins in Glutamatergic Circuits: Identification of Common Signaling Pathways and Molecular Targets in Anxiety and Major Depressive Disorders (GAPsy) nanUNKNOWN
Clinical Study of 18F-FAPI-RGD in Breast Tumors nanCOMPLETED
The Role of the Novel 99mTc-NC100692 Tracer in Patients at High Risk or Known Breast Cancer nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a ITGA6 binder may also engage these)

ProteinNameSimilarity
P26008 1.000 P26008 →
Q61739 0.998 Q61739 →
Q91687 0.994 Q91687 →
P26007 0.994 P26007 →
Q2QLA9 0.993 Q2QLA9 →
Q75ZY9 0.992 Q75ZY9 →
Q09YK0 0.992 Q09YK0 →
Q108U6 0.992 Q108U6 →
Q07DZ1 0.992 Q07DZ1 →
ITGAV Integrin alpha-V 0.991 landscape →
P80746 0.990 P80746 →
P97523 0.990 P97523 →
Q2QLH6 0.990 Q2QLH6 →
Q03600 0.990 Q03600 →
P16056 0.989 P16056 →
A0M8R7 0.989 A0M8R7 →
P43406 0.988 P43406 →
MET Hepatocyte growth factor receptor 0.988 landscape →
Q9V7A4 0.987 Q9V7A4 →
Q09YH7 0.987 Q09YH7 →
O42236 0.987 O42236 →
Q06274 0.987 Q06274 →
A2A863 0.987 A2A863 →
EPHA5 Ephrin type-A receptor 5 0.986 landscape →
Q62181 0.986 Q62181 →
Q09YN5 0.986 Q09YN5 →
Q8SQ75 0.985 Q8SQ75 →
Q9UKX5 0.985 Q9UKX5 →
Q09YL1 0.985 Q09YL1 →
Q91735 0.985 Q91735 →