SCHEMBL17014126

SCHEMBL17014126

c1ccc(-c2c3ccccc3c(-c3cccc(-c4nc(-c5cccc(-c6cccnc6)c5)cc(-c5ccccn5)n4)c3)c3ccccc23)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.47
KMO O15229 1/20 0.45
GRM5 P41594 2/20 0.45
TSHR P16473 3/20 0.43
NPC1 O15118 1/20 0.43
TP53 P04637 1/20 0.43
PKM P14618 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CYP19A1 P11511 2/20 0.42
DHODH Q02127 1/20 0.40
PIM1 P11309 1/20 0.40
PIM2 Q9P1W9 1/20 0.40
SCN5A Q14524 1/20 0.39
SCN9A Q15858 1/20 0.39
CYP11B1 P15538 2/20 0.39
CYP17A1 P05093 1/20 0.39
CYP11B2 P19099 1/20 0.39
GBA1 P04062 2/20 0.38
MEN1 O00255 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17013974 0.93 CYP2A6 (0.56) CYP2A6KMOGRM5TSHRNPC1
SCHEMBL17014036 0.93 CYP2A6 (0.56) CYP2A6KMOGRM5TSHRNPC1
SCHEMBL17014072 0.92 CYP2A6 (0.54) CYP2A6KMOGRM5TSHRNPC1
SCHEMBL17369022 0.92 CYP19A1 (0.49) CYP2A6KMOTSHRCYP19A1DHODH
SCHEMBL19797626 0.91 CYP2A6 (0.52) CYP2A6KMOGRM5TSHRNPC1
SCHEMBL17013880 0.90 KMO (0.48) CYP2A6KMOTSHRRAB9ACYP19A1
SCHEMBL17014032 0.90 KMO (0.48) CYP2A6KMOTSHRRAB9ACYP19A1
SCHEMBL17013981 0.90 CYP19A1 (0.51) KMOTSHRCYP19A1DHODHCYP11B1
SCHEMBL19797630 0.90 CYP19A1 (0.51) CYP2A6KMOTSHRCYP19A1DHODH
SCHEMBL17014037 0.90 CYP19A1 (0.51) KMOTSHRCYP19A1DHODHCYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10230051-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2019-03-12 US disclosed
US-20150236264-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-08-20 US disclosed
US-20150236264-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-08-20 US disclosed