SCHEMBL17014571

SCHEMBL17014571

c1ccc(-c2cc(-c3ccc(-c4ccc5ccc6ccccc6c5n4)cc3)c(-c3ccccc3)c3c2-c2cccc4cccc-3c24)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.39
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
PIM1 P11309 2/20 0.37
PIM2 Q9P1W9 1/20 0.37
ENPP1 P22413 3/20 0.35
ENPP3 O14638 1/20 0.35
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
TNF P01375 1/20 0.34
CYP1A1 P04798 1/20 0.33
CYP1B1 Q16678 1/20 0.33
PLAUR Q03405 1/20 0.33
CDK4 P11802 1/20 0.33
CCND1 P24385 1/20 0.33
ACACA Q13085 1/20 0.33
RAB9A P51151 1/20 0.33
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17014579 0.88 KDM4E (0.31) PARP1KDM4EALDH1A1MAPTHPGD
SCHEMBL17014572 0.87 TOP1 (0.43) PARP1KDM4EALDH1A1MAPTHPGD
SCHEMBL17014577 0.86 TOP1 (0.42) PARP1KDM4EALDH1A1MAPTHPGD
SCHEMBL12731969 0.81 TOP1 (0.41) PARP1KDM4EMAPTPIM1PIM2
SCHEMBL19768464 0.80 ENPP1 (0.47) PARP1KDM4EALDH1A1MAPTHPGD
SCHEMBL2140937 0.80 ALDH1A1 (0.40) KDM4EALDH1A1MAPTHPGDENPP1
SCHEMBL76389 0.80 ALDH1A1 (0.44) PARP1KDM4EALDH1A1MAPTHPGD
SCHEMBL2158220 0.80 ALDH1A1 (0.47) PARP1KDM4EALDH1A1MAPTHPGD
SCHEMBL19768252 0.80 ALDH1A1 (0.41) PARP1KDM4EALDH1A1MAPTHPGD
SCHEMBL17014582 0.79 MEN1 (0.49) KDM4EALDH1A1MAPTHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10680182-B2 Fluoranthene compound, and organic electronic device comprising same LG CHEM, LTD. (KR) 2020-06-09 US disclosed
EP-2924020-B1 FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2019-01-16 EP disclosed
EP-2924020-A1 FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG Chem, Ltd. (KR) 2015-09-30 EP disclosed
US-20150236273-A1 FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2015-08-20 US disclosed
US-20150236273-A1 FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2015-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10680182-B2 Fluoranthene compound, and organic electronic device comprising same AFF2, ESR1, AFF4 PARP1 1043/4885KDM4E 870/4885ALDH1A1 1216/4885
US-20150236273-A1 FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME AFF2, ESR1, AFF4 PARP1 1043/4885KDM4E 870/4885ALDH1A1 1216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.