Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 7/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | FABP1 | P07148 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17014579 | 0.89 | KDM4E (0.31) | PIM1PIM2KDM4EMAPTALDH1A1 | |
| SCHEMBL17014572 | 0.89 | TOP1 (0.43) | TOP1BRD4PIM1PIM2KDM4E | |
| SCHEMBL17014577 | 0.88 | TOP1 (0.42) | TOP1BRD4PIM1PIM2KDM4E | |
| SCHEMBL11992196 | 0.86 | AVPR2 (0.34) | TOP1BACE1BRD4PIM1PIM2 | |
| SCHEMBL12731969 | 0.85 | TOP1 (0.41) | TOP1BRD4PIM1PIM2KDM4E | |
| SCHEMBL11992201 | 0.84 | TOP1 (0.33) | TOP1BACE1BRD4PIM1PIM2 | |
| SCHEMBL13311191 | 0.82 | CCR1 (0.47) | KDM4EMAPTTDP1GMNNLMNA | |
| SCHEMBL17014611 | 0.81 | TOP1 (0.42) | TOP1BRD4PIM1PIM2KDM4E | |
| SCHEMBL19768069 | 0.81 | BACE1 (0.38) | TOP1BACE1BRD4FABP1KDM4E | |
| SCHEMBL23839634 | 0.80 | CCR1 (0.37) | BACE1BRD4KDM4EMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10680182-B2 | Fluoranthene compound, and organic electronic device comprising same | LG CHEM, LTD. (KR) | 2020-06-09 | — | — | US | disclosed |
| EP-2924020-B1 | FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME | LG CHEMICAL LTD (KR) | 2019-01-16 | — | — | EP | disclosed |
| EP-2924020-A1 | FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME | LG Chem, Ltd. (KR) | 2015-09-30 | — | — | EP | disclosed |
| US-20150236273-A1 | FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2015-08-20 | — | — | US | disclosed |
| US-20150236273-A1 | FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2015-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10680182-B2 | Fluoranthene compound, and organic electronic device comprising same | AFF2, ESR1, AFF4 | TOP1 2130/4885BACE1 1931/4885BRD4 1042/4885 |
| US-20150236273-A1 | FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME | AFF2, ESR1, AFF4 | TOP1 2130/4885BACE1 1931/4885BRD4 1042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.