SCHEMBL17014608

SCHEMBL17014608

CC1(C)OB(c2cccc(-c3cc(-c4ccccc4)c4c(c3-c3ccccc3)-c3cccc5cccc-4c35)c2)OC1(C)C

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 7/20 0.43
LPL P06858 6/20 0.43
PDGFRB P09619 1/20 0.33
KDR P35968 1/20 0.33
IRAK4 Q9NWZ3 1/20 0.31
TYMS P04818 1/20 0.31
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
CASP1 P29466 1/20 0.30
CASP7 P55210 1/20 0.30
HIF1A Q16665 1/20 0.30
HSD17B10 Q99714 1/20 0.30
PRMT5 O14744 1/20 0.30
WDR77 Q9BQA1 1/20 0.30
P4HB P07237 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17122838 0.94 LIPG (0.42) LIPGLPLPDGFRBKDRIRAK4
SCHEMBL17014607 0.92 LIPG (0.55) LIPGLPLPDGFRBKDRIRAK4
SCHEMBL25681129 0.89 LIPG (0.51) LIPGLPLPDGFRBKDRIRAK4
SCHEMBL30024835 0.87 LIPG (0.53) LIPGLPLPDGFRBKDRIRAK4
SCHEMBL18180909 0.87 LIPG (0.53) LIPGLPLPDGFRBKDRIRAK4
SCHEMBL18181002 0.85 LIPG (0.50) LIPGLPLPDGFRBKDRIRAK4
SCHEMBL31454000 0.85 LIPG (0.50) LIPGLPLPDGFRBKDRIRAK4
SCHEMBL25361434 0.84 LIPG (0.40) LIPGLPLPDGFRBKDRTYMS
SCHEMBL30486014 0.83 LIPG (0.54) LIPGLPLPDGFRBKDRIRAK4
SCHEMBL13299967 0.82 LIPG (0.48) LIPGLPLPDGFRBKDRIRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10680182-B2 Fluoranthene compound, and organic electronic device comprising same LG CHEM, LTD. (KR) 2020-06-09 US disclosed
US-20150236273-A1 FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2015-08-20 US disclosed
US-20150236273-A1 FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2015-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10680182-B2 Fluoranthene compound, and organic electronic device comprising same AFF2, ESR1, AFF4 LIPG 1793/4885LPL 2006/4885PDGFRB 3553/4885
US-20150236273-A1 FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME AFF2, ESR1, AFF4 LIPG 1793/4885LPL 2006/4885PDGFRB 3553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.